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方案
98%
折射率
n20/D 1.4995 (lit.)
沸点
157-159 °C/752 mmHg (lit.)
密度
1.188 g/mL at 25 °C (lit.)
SMILES字符串
Cc1cc(Cl)ccc1F
InChI
1S/C7H6ClF/c1-5-4-6(8)2-3-7(5)9/h2-4H,1H3
InChI key
JOXXHDGUTVUBDL-UHFFFAOYSA-N
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危险分类
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
120.2 °F - closed cup
闪点(°C)
49 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
K L Shepard et al.
Journal of medicinal chemistry, 34(10), 3098-3105 (1991-10-01)
For several decades a tantalizing goal for the treatment of primary open-angle glaucoma has been the development of a topically active carbonic anhydrase inhibitor. Recent results from several research groups indicate that considerable progress has been made toward this objective.
Dorus Heijnen et al.
Organic letters, 17(9), 2262-2265 (2015-04-15)
The palladium-catalyzed direct cross-coupling of a range of organic chlorides and bromides with the bifunctional C(sp(3))-(trimethylsilyl)methyllithium reagent is reported. The use of Pd-PEPPSI-IPent as the catalyst allows for the preparation of structurally diverse and synthetically versatile benzyl- and allylsilanes in
H Kanno et al.
Chemical & pharmaceutical bulletin, 40(8), 2049-2054 (1992-08-01)
New 1,4-dihydropyridine derivatives bearing a 4-(disubstituted phenyl) ring and an aminoethyl ester or an amino-2,2-dimethyl-propyl ester were synthesized and their antihypertensive activities were examined in normotensive rats and spontaneously hypertensive rats. The effects of phenyl substituents and ester groups on
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