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方案
95%
表单
solid
mp
53-55 °C (lit.)
官能团
anhydride
ester
SMILES字符串
CCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCC
InChI
1S/C28H54O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27(29)31-28(30)26-24-22-20-18-16-14-12-10-8-6-4-2/h3-26H2,1-2H3
InChI key
RCRYHUPTBJZEQS-UHFFFAOYSA-N
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一般描述
应用
Myristic anhydride may be used in the following studies:
- As a reactant to synthesize cholesteryl myristate by reacting with cholesterol.[3]
- As a reactant in the synthesis of 1,2-dimyristoyl-sn-glycero-3-phosphocholine by acylating sn-glycero-3-phosphocholine.[4]
- As a reagent in the synthesis of 3-(bis-{2-(tert-butyldimethylsilyloxy)ethyl}amino)propane-1,2-diol, an intermediate of cationic lipid.[5]
- As a reactant to synthesize neryl myristate by reacting with nerol.[6]
- As a reagent to synthesize myristoylated t-butylglutamic acid by myristoylation of γ-tert-butoxy-glutamic acid.[7]
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Neryl myristate from the acarid mite, Aleuroglyphus ovatus (acarina, acaridae).
Leal WS, et al.
Agricultural and Biological Chemistry, 52(5), 1299-1300 (1988)
K M Patel et al.
Journal of lipid research, 20(5), 674-677 (1979-07-01)
A high-yield synthesis of saturated, unsaturated, and short chain phosphatidylcholines from sn-glycero-3-phosphocholine is described. The procedure offers advantages over other reported procedures for the synthesis of phosphatidylcholine in that the large-scale synthesis and purification can be achieved in a minimum
Michael H Nantz et al.
Molecular pharmaceutics, 7(3), 786-794 (2010-03-18)
We, and others, have observed that the structure of cationic lipids appears to have a significant effect on the transfection efficacy of optimized nucleic acid/cationic lipid complexes (lipoplexes) used for in vitro and in vivo gene delivery and expression. Although
Reactions of fatty acid chlorides. I. Preparation of fatty acid anhydrides.
Sonntag NOV, et al.
Journal of the American Oil Chemists' Society, 31(4), 151-157 (1954)
Bhupender S Chhikara et al.
Tetrahedron letters, 53(39), 5335-5337 (2012-11-24)
Designing microbicidal gels of anti-HIV drugs for local application to prevent HIV infection is a subject of major interest. 3'-Fluoro-3'-deoxythymidine (FLT), a nucleoside reverse transcriptase inhibitor (NRTI), was conjugated with a N-myristoyl glutamate scaffold. The conjugate showed gelation at 1%
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