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Merck

371785

Sigma-Aldrich

5-羟基间苯二甲酸二甲酯

98%

别名:

5-羟基苯-1,3-二羧酸二甲酯

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10 G
$62.00
50 G
$199.00

About This Item

线性分子式:
HOC6H3-1,3-(CO2CH3)2
CAS号:
分子量:
210.18
Beilstein:
2650120
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

$62.00


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方案

98%

表单

powder

mp

162-164 °C (lit.)

官能团

ester

SMILES字符串

COC(=O)c1cc(O)cc(c1)C(=O)OC

InChI

1S/C10H10O5/c1-14-9(12)6-3-7(10(13)15-2)5-8(11)4-6/h3-5,11H,1-2H3

InChI key

DOSDTCPDBPRFHQ-UHFFFAOYSA-N

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一般描述

5-羟基间苯二甲酸二甲酯与烯丙基缩水甘油醚进行碱催化的亲核环氧乙烷开环加成反应,生成间苯二甲酸的 5-取代衍生物。[1]已经研究了第三组分(即一系列的 1,ω-链烷二醇)对 5-羟基间苯二甲酸二甲酯与聚乙二醇的共聚反应的影响。[2]已经报道了脂肪酶催化 5-羟基间苯二甲酸二甲酯与聚乙二醇的缩聚反应。[3]

应用

衍生自 5-羟基间苯二甲酸二甲酯的新型结构单元已用于通过 O-烯丙基化/Claisen 重排反应来制备空间拥挤的聚醚树枝状分子。[4]5-羟基间苯二甲酸二甲酯可用于制备:
  • 环磷腈的双(phebox)衍生物[5]
  • 5- {2- [2-(2-甲氧基乙氧基)乙氧基]乙氧基}苯-1,3-二羧酸二甲酯[6]
  • 带有三乙二醇型极性头基的富勒烯衍生物[6]

象形图

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警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

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Rajesh Kumar et al.
Molecular diversity, 6(3-4), 287-295 (2004-04-08)
The use of enzymes in synthetic applications has increased dramatically in the recent years and the field of polymer science is part of this trend. Synthesis of a variety of polymers using lipase catalyzed (Candida antarctica) polymerization reactions has led
Biocatalytic ?green? Synthesis of PEG-based aromatic polyesters: Optimization of the substrate and reaction conditions.
Kumar R, et al.
Green Chemistry, 6(10), 516-520 (2004)
Jeny Karabline et al.
Organic & biomolecular chemistry, 10(24), 4788-4794 (2012-05-19)
Up to third-generation sterically crowded polyether dendrons were prepared on a solid support, using a novel building block derived from dimethyl 5-hydroxyisophthalate via O-allylation/Claisen rearrangement key steps. These dendrons underwent smooth disassembly to monomers, when subjected to acidic solution. The
Denis Nilov et al.
Tetrahedron letters, 55(36), 5078-5081 (2014-08-26)
In the course of development of novel capping ligands with variable steric factor, which will be used as an organic coating for metal oxide nanoparticles, a base-catalyzed nucleophilic oxirane ring-opening addition reaction between dimethyl 5-hydroxyisophthalate and allyl glycidyl ether was
Dheeraj Kumar et al.
Dalton transactions (Cambridge, England : 2003), 43(37), 13899-13912 (2014-08-12)
Chiral oxazoline based bi and hexadentate ligands built on cyclophosphazene cores have been synthesized and characterized. (NPPh2)2[NP(m-OC6H4C(O)OCH3)2] (1) was prepared by the reaction of gem-(NPPh2)2(NPCl2) with methyl-3-hydroxy benzoate in the presence of Cs2CO3. Compound 1 was converted to the dicarboxylic

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