所有图片(1)
About This Item
经验公式（希尔记法）:
C19H23NO4 · 0.3CHCl3
CAS号:
分子量:
365.20
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22
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藥物控制
regulated under CDSA - not available from Sigma-Aldrich Canada
雜質
0.3 mol chloroform of crystallization
mp
180 °C (dec.) (lit.)
官能基
ether
ketone
SMILES 字串
COC1=CC2[C@@H]3Cc4ccc(OC)c(O)c4[C@]2(CCN3C)CC1=O
InChI
1S/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1
InChI 密鑰
INYYVPJSBIVGPH-QHRIQVFBSA-N
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訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Liver,Kidney, Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Lihua Zhu et al.
Molecular and cellular biochemistry, 373(1-2), 53-62 (2012-10-16)
Sinomenine, a pure alkaloid extract from Sinomenium acutum, has anti-inflammatory and immunoregulatory functions. This study investigated the efficiency and the signalling pathways involved in the effect of sinomenine on vascular smooth muscle cell (VSMC) dedifferentiation in response to platelet-derived growth
Xiao-Ling Wang et al.
Journal of Asian natural products research, 13(6), 523-528 (2011-05-31)
Two new morphinane alkaloids, 1-hydroxy-10-oxo-sinomenine (1) and 4,5-epoxy-14-hydroxy sinomenine N-oxide (2), have been isolated from the stems of Sinomenium acutum. Their structures were established by various spectral analyses, especially 2D NMR experiments. The structure of 2 was confirmed by single
Lie Xiong et al.
Immunotherapy, 4(8), 785-791 (2012-09-06)
To evaluate the immunosuppressive efficacy of alkaloid sinomenine (SIN) and the synergistic effects in combination with cyclosporin A (CsA) in acute rejection after rat renal allograft. Animals were treated with saline in group 1, SIN (30 mg/kg/d) in group 2
Daojin Li et al.
Journal of photochemistry and photobiology. B, Biology, 117, 126-131 (2012-11-01)
The binding of sinomenine to human serum albumin (HSA) in aqueous solution in the absence and presence of urea has been studied by fluorescence and the three-dimensional (3D) fluorescence at pH 7.40. Subdomain IIA binding site of human serum albumin
David Pérol et al.
BMC cancer, 12, 603-603 (2012-12-19)
Chemotherapy induced nausea and vomiting (CINV) remains a major problem that seriously impairs the quality of life (QoL) in cancer patients receiving chemotherapy regimens. Complementary medicines, including homeopathy, are used by many patients with cancer, usually alongside with conventional treatment.
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