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Merck

363081

Sigma-Aldrich

聚乙烯醇

average Mw 85,000-124,000, 87-89% hydrolyzed

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About This Item

线性分子式:
[-CH2CHOH-]n
CAS号:
MDL號碼:
分類程式碼代碼:
12352104
NACRES:
NA.23

品質等級

形狀

powder or crystals

分子量

average Mw 85,000-124,000

降落球

23-27 cP, 4 % in H2O(20 °C)(lit.)

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI 密鑰

IMROMDMJAWUWLK-UHFFFAOYSA-N

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一般說明

聚乙烯醇(PVA)是一种线性 亲水性合成聚合物,其主链仅由碳原子组成。 由于其惰性和稳定性,它被认为是安全和生物相容的。 它在厌氧和好氧条件下都是可生物降解的。由于 其独特的粘附性、安全性、强度、 成膜性、溶胀性和非致癌性等特性,它被广泛应用于 纸张、粘合剂、食品、生物医学和制药行业。部分水解的 PVA(87–89%)更易溶于水,并且对疏水表面具有更大的柔韧性和粘附性。

應用

PVA 对于 用于药物递送系统的聚合物具有显著的性能,例如高 表面稳定性和低蛋白质吸附。PVA 用在固体 分散体中防止晶体形成并提高药物溶解度。 它也可以用作造粒液,以防止晶体生长和 成核缓慢。与它的共聚物一起,它可以用于 亲水性和疏水性药物。 PVA 水凝胶和 微粒可用于癌症药物的药物输送系统。

PVA 可作为 表面稳定剂用于制备四环素缓释药物递送 载体。

高浓度藻酸盐/聚乙烯醇 (PVA)生物墨水可用于制备 3D 生物打印多孔支架。PVA 溶胶 从印刷支架的部分扩散产生了大量的于大量样品的并行测试。 微孔。

PVA 也可以作为水溶性聚合物模板, 通过原位聚合合成纳米聚吡咯。PVA 在水中产生稳定的聚吡咯纳米球分散体,纳米球的大小 取决于 PVA 的分子量和浓度。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

No data available

閃點(°C)

No data available

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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International journal of pharmaceutics, 600, 120478-120478 (2021-03-17)
Polyvinyl alcohol (PVA) is a biodegradable semicrystalline synthetic polymer that has been used for biomedical applications for several years. In the pharmaceutical area, PVA has been widely used to prepare solid dispersions to improve the solubility of drugs. Furthermore, it
Gang Wang et al.
PloS one, 6(11), e27605-e27605 (2011-11-24)
Mucosal vaccination has been demonstrated to be an effective means of eliciting protective immunity against aerosol infections of foot and mouth disease virus (FMDV) and various approaches have been used to improve mucosal response to this pathogen. In this study
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Biofabrication, 5(1), 015014-015014 (2013-02-07)
A tetragonal polyvinyl alcohol (PVA) scaffold with 3D orthogonal periodic porous architecture was fabricated via selective laser sintering (SLS) technology. The scaffold was fabricated under the laser power of 8 W, scan speed of 600 mm min(-1), laser spot diameter of 0.8 mm

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