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About This Item
经验公式（希尔记法）:
C9H18N2O2
CAS号:
分子量:
186.25
Beilstein:
879985
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
推荐产品
化驗
97%
形狀
solid
mp
43-47 °C (lit.)
SMILES 字串
CC(C)(C)OC(=O)N1CCNCC1
InChI
1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3
InChI 密鑰
CWXPZXBSDSIRCS-UHFFFAOYSA-N
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一般說明
1-Boc-哌嗪是-Boc保护的哌嗪。1-Boc-哌嗪与芳基碘的CuBr/1，1′交叉偶联。研究报道了铋-2-萘酚（催化剂）和K3PO4（碱）。1-Boc-哌嗪与芳基卤化物发生布赫华-哈特威格偶联反应。碘催化无溶剂N-Boc保护可制备80%产率的1-Boc-哌嗪。
應用
1-Boc-哌嗪可用于：
- （m·-苯氧基）苯基取代哌嗪衍生物系列的制备
- 通过活性阳离子开环聚合合成α,β-聚（2-噁唑啉）脂聚合物期间的终止步骤。
- 单取代哌嗪的制备，例如吲唑脱氧核糖核酸回旋酶抑制剂的合成
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
235.4 °F - closed cup
閃點（°C）
113 °C - closed cup
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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