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Merck

337757

Sigma-Aldrich

N-(磷酰基甲基)甘氨酸

96%, for peptide synthesis

别名:

草甘膦

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250 MG
$59.00
1 G
$104.00
5 G
$357.00

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250 MG
$59.00
1 G
$104.00
5 G
$357.00

About This Item

线性分子式:
(HO)2P(O)CH2NHCH2CO2H
CAS号:
分子量:
169.07
Beilstein:
2045054
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

$59.00


请联系客服了解存货情况

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产品名称

N-(磷酰基甲基)甘氨酸, 96%

方案

96%

表单

powder

反应适用性

reaction type: solution phase peptide synthesis

mp

230 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

OC(=O)CNCP(O)(O)=O

InChI

1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)

InChI key

XDDAORKBJWWYJS-UHFFFAOYSA-N

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一般描述

N-(磷甲基)甘氨酸(草甘膦)是一种广谱、非选择性的内吸性除草剂。[1][2]它在抑制参与芳香族氨基酸生物合成的 5-烯醇丙酮酸莽草酸-3-磷酸合成酶的活性中起重要作用。[3][4]草甘膦具有螯合性能,可与多种金属离子形成配位络合物。[5][6][1]

应用

  • 水污染分析:Campanale等人评估了河水和沉积物中的草甘膦和AMPA杀虫剂,提供了有关N-(膦酰基甲基)甘氨酸衍生物的环境分布和持久性的关键数据。该研究为环境污染物的有效监测和管理提供支持(Campanale et al., 2024)。
  • 公共卫生研究:以N-(膦酰基甲基)甘氨酸为标志物对农民进行了草甘膦暴露的尿生物监测。该研究可帮助我们理解职业暴露风险,并为卫生安全指南的制定提供支持 (Chang et al., 2024)。

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Dermal - Aquatic Chronic 2 - Eye Dam. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Glyphosate: a once?in?a?century herbicide.
Duke S O and Powles S B
Pest Management Science, 64(4), 319-325 (2008)
Hui Gao et al.
Journal of applied toxicology : JAT, 39(8), 1096-1107 (2019-03-26)
Glyphosate-based herbicides have been used worldwide for decades and have been suggested to induce nephrotoxicity, but the underlying mechanism is not yet clear. In this study, we treated a human renal proximal tubule cell line (HK-2) with glyphosate for 24 hours
Biochemical effects of glyphosate (N-(phosphonomethyl) glycine)[Lemna, higher plants, phenylalanine ammonialyase].
Hoagland R E and Duke S O
ACS Symp. Ser. (1982)
The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase.
Steinrucken H C and Amrhein N
Biochemical and Biophysical Research Communications, 94(4), 1207-1212 (1980)
The complex chemistry of N-(phosphonomethyl) glycine (glyphosate): preparation and characterization of the ammonium, lithium, sodium (4 polymorphs) and silver (I) complexes.
Sagatys D S, et al.
J. Chem. Soc., Dalton Trans., 19, 3404-3410 (2000)

实验方案

EPA Method 547 outlines the analysis of glyphosate in drinking water by direct aqueous injection HPLC, post column derivatization, and fluorescence detection

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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