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290858

Sigma-Aldrich

壬基酚

technical grade, mixture of ring and chain isomers

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25 ML
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25 ML
$81.60

About This Item

经验公式（希尔记法）:
C15H24O
CAS号:
84852-15-3
分子量:
220.35
Beilstein:
2047450
EC 号:
284-325-5
MDL编号:
MFCD00002396
UNSPSC代码:
12352100
PubChem化学物质编号:
24857492
NACRES:
NA.22

$81.60

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等级

technical grade

质量水平

200

折射率

n20/D 1.511 (lit.)

溶解性

water: slightly soluble 4.9 mg/L±0.4 mg/L

密度

0.937 g/mL at 25 °C (lit.)

SMILES字符串

CCCCCCCCCc1ccc(O)cc1

InChI

1S/C15H24O/c1-13(2)7-5-3-4-6-8-14-9-11-15(16)12-10-14/h9-13,16H,3-8H2,1-2H3

InChI key

JSFITYFUKSFPBZ-UHFFFAOYSA-N

基因信息

mouse ... Esr1(13982)
rat ... Ar(24208)

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相关类别

一般描述

壬基酚是一种有毒的异生素化合物，属于内分泌干扰物，能够干扰许多生物的激素系统[1]。已有报道称壬基酚可作为抗雄激素用于酵母检测系统[2]。已研究报道了壬基酚的抗雄激素作用的分子机制[2]。

应用

  • 新出现污染物的氯化处理在饮用水废水回用中的应用：消毒副产物形成、雌激素活性和细胞毒性：研究饮用水废水回用中壬基酚氯化过程中消毒副产物的形成、雌激素活性和细胞毒性，为水处理安全方案提供见解（Cochran et al., 2024）。
  • 通过光电、电致变色和光谱信号耦合三模传感器用于壬基酚的灵敏可视化检测：描述用于检测壬基酚的灵敏三模传感器的开发，集成了光电化学、电致变色和光谱信号，可用于环境监测和工业过程控制（Cao et al., 2023）。

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

>235.4 °F - closed cup

闪点(°C)

> 113 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW3202
MKCT1575
MKCV4134
MKCQ1752
MKCR3252

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A Soares et al.
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Hyun Ju Lee et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 40-46 (2003-06-14)
By using a yeast detection system for androgenic and antiandrogenic effects of chemicals, we identified bisphenol A (BPA) and nonylphenol (NP) as antiandrogens. In this study, we report molecular mechanisms for the antiandrogenic action of BPA and NP. In the
C Uguz et al.
Andrologia, 47(8), 910-919 (2014-10-04)
The objective of this study was to determine the effects of nonylphenol (NP) on viability of ram and boar sperm in vitro. Ram or boar spermatozoa were exposed to 1, 10, 100, 250 and 500 μg NP ml(-1) for 1, 2, 3 or
Maurizio Forte et al.
Ecotoxicology and environmental safety, 180, 412-419 (2019-05-21)
Estrogens play a role in the patho-physiology of the prostate. In the present work we studied the effects of nonylphenol (NP), a xenoestrogen, on human adenocarcinoma prostate cells (LNCaP). In order to understand molecular and cellular involvement, we observed the
Tomasz Janicki et al.
Bioresource technology, 200, 223-229 (2015-10-23)
Nonylphenol (NP), 4-tert-octylphenol (4-t-OP) and 4-cumylphenol (4-CP) are pollutants that are known as endocrine disruptors mainly due to their estrogen-mimicking activity. These phenolic substances are used in a wide range of industrial and commercial applications. In the present study, biodegradation
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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