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Merck

290440

Sigma-Aldrich

3,5-二氟苯乙酸

99%

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About This Item

线性分子式:
F2C6H3CH2CO2H
分子量:
172.13
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

mp

68-70 °C (lit.)

SMILES 字串

OC(=O)Cc1cc(F)cc(F)c1

InChI

1S/C8H6F2O2/c9-6-1-5(3-8(11)12)2-7(10)4-6/h1-2,4H,3H2,(H,11,12)

InChI 密鑰

IGGNSAVLXJKCNH-UHFFFAOYSA-N

一般說明

3,5-Difluorophenylacetic acid is an important pharmaceutical intermediate.

應用

3,5-Difluorophenylacetic acid has been used in the synthesis of:
  • N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-L-phenylglycine tert-butyl ester
  • N-acylalanine

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析证书(COA)

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访问文档库

Gilles Quéléver et al.
Organic & biomolecular chemistry, 3(13), 2450-2457 (2005-06-25)
Inhibition of gamma-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce pathogenic Abeta peptides, is an attractive approach for the treatment of Alzheimer's disease. We designed a gamma-secretase inhibitor bearing an ascorbic
Synthesis of a tetrahydroimidazo [2', 1': 2, 3] thiazolo [5, 4-c] pyridine derivative with Met inhibitory activity.
Amat M, et al.
ARKIVOC (Gainesville, FL, United States), 3, 145-151 (2010)
Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy.
Kowalczyk BA.
Synthesis, 1997(12), 1411-1414 (1997)

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