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Merck

255920

Sigma-Aldrich

1,1'-(偶氮二羰基)二哌啶

99%

别名:

1,1′-偶氮双(NN-五亚甲基甲酰胺), ADD, NSC 356027, SR 4077, 偶氮二甲酰二哌啶

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About This Item

经验公式(希尔记法):
C12H20N4O2
CAS号:
分子量:
252.31
Beilstein:
261917
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

solid

mp

134-136 °C (lit.)

SMILES 字串

O=C(\N=N\C(=O)N1CCCCC1)N2CCCCC2

InChI

1S/C12H20N4O2/c17-11(15-7-3-1-4-8-15)13-14-12(18)16-9-5-2-6-10-16/h1-10H2/b14-13+

InChI 密鑰

OQJBFFCUFALWQL-BUHFOSPRSA-N

應用

制备用反应物:
  • 多氟烷基化三吡唑甲烷配体

  • 通过 Mitsunobu 糖基化的 (-)-潮霉素 A
  • 通过 Mitsunobu 反应光学活性 α,α-二取代氨基酸
  • 通过 [2 + 2] 环加成反应合成叠氮-β-内酰胺类
  • 糖基二硫化物
  • 吡啶醚类 PPAR 激动剂
  • 组合新糖肽合成的 S-糖基氨基酸构件
  • 组胺 H3 受体拮抗剂

反应物用于:
  • Mitsunobu 翻转反应
广泛用于 Mitsunobu 反应的试剂
用于研究芳基硼酸通过铜催化加成得到偶氮二甲酸衍生物,从而生成芳基取代酰肼的反应。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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E A Bump et al.
International journal of radiation oncology, biology, physics, 29(2), 249-253 (1994-05-15)
To determine whether biological effects of radiation, such as apoptosis, that differ from classical clonogenic cell killing, can be modified with agents that would not be expected to modify classical clonogenic cell killing. This would expand the range of potential
Tetrahedron Letters, 34, 1639-1639 (1993)
Dougherty, J.M.; et al.
Tetrahedron, 61, 6218-6218 (2005)
Takeshi Uemura et al.
The Journal of organic chemistry, 70(21), 8631-8634 (2005-10-08)
The addition of arylboronic acids 1 to azodicarboxylates 2 in the presence of a catalytic amount of a copper salt under mild reaction conditions gives aryl-substituted hydrazines 3 in high yields. The reaction is tolerant of a wide variety of
M A Baker et al.
Radiation research, 113(2), 346-355 (1988-02-01)
The mechanism of radiosensitization by diazenedicarboxylic acid bis(N),N-piperidide (SR 4077), a less toxic analog of diamide, was studied using Chinese hamster ovary cells. SR 4077 gave an average SER of 1.58 for postirradiation incubations of 0.5, 1.0, or 2.0 h.

相关内容

One of the most powerful and widely used carboncarbon bond forming reactions in organic synthesis is the Mitsunobu reaction.

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