254606

(S)-(-)-2,2-二甲基-1,3-二氧戊环-4-羧酸甲酯

96%

• 别名: α,β-异亚丙基-L-甘油酸甲酯, 2,3-O-异亚丙基-L-甘油酸甲酯, 甲基α,β-异亚丙基-L-甘油酸酯
• 经验公式（希尔记法）: C₇H₁₂O₄
• CAS号: 60456-21-5
• 分子量: 160.17
• Beilstein: 4292352
• MDL號碼: MFCD00066526
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24855396
• NACRES: NA.22

属性

• 化驗: 96%
• 形狀: liquid
• 光學活性: [α]20/D −8.5°, c = 1.5 in acetone
• 光學純度: ee: ≥96.0% (GLC)
• 折射率: n20/D 1.425 (lit.)
• bp: 84-86 °C/15 mmHg (lit.)
• 密度: 1.106 g/mL at 25 °C (lit.)
• SMILES 字串: COC(=O)[C@@H]1COC(C)(C)O1
• InChI: 1S/C7H12O4/c1-7(2)10-4-5(11-7)6(8)9-3/h5H,4H2,1-3H3/t5-/m0/s1
• InChI 密鑰: DOWWCCDWPKGNGX-YFKPBYRVSA-N

说明

應用

(−)-Methyl (S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate can be used:

• As a chiral building block to make the key tetrahydrofuran subunit of (−)-gymnodimine, a marine algal toxin.
• To prepare an enedione by reacting with dimethyl methylphosphonate, BuLi, and phenylglyoxal, which in turn is used to synthesize cyclopentenone derivatives.
• As a starting material for the preparation of (S)-4,5-dihydroxy-2,3-pentanedione (DPD), a precursor for autoinducer (AI)-2 in bacteria.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 172.4 °F - closed cup
• 閃點（°C）: 78 °C - closed cup
• 個人防護裝備: Eyeshields, Gloves, type ABEK (EN14387) respirator filter