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Merck

249408

Sigma-Aldrich

2,6-二氟苯甲酰氯

99%

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About This Item

线性分子式:
F2C6H3COCl
CAS号:
分子量:
176.55
Beilstein:
639438
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

化驗

99%

形狀

liquid

折射率

n20/D 1.501 (lit.)

bp

72-77 °C/13 mmHg (lit.)

密度

1.404 g/mL at 25 °C (lit.)

SMILES 字串

Fc1cccc(F)c1C(Cl)=O

InChI

1S/C7H3ClF2O/c8-7(11)6-4(9)2-1-3-5(6)10/h1-3H

InChI 密鑰

QRHUZEVERIHEPT-UHFFFAOYSA-N

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應用

2,6-Difluorobenzoyl chloride has been used in:
  • the preparation of series of novel 2-aryl substituted 4H-3,1-benzoxazin-4-ones
  • regioselective synthesis of 3,6-disubstituted-2-aminoimidazo[1,2-a]pyridine
  • Friedel-Crafts acylation reaction of toluene, anisol, thioanisol, 4-phenoxyacetophenone and N,N-diacetyl-4-phenoxyaniline

象形圖

FlameCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

114.8 °F - closed cup

閃點(°C)

46 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析证书(COA)

Lot/Batch Number

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P Jakobsen et al.
Bioorganic & medicinal chemistry, 8(8), 2095-2103 (2000-09-26)
The synthesis of a series of novel 2-aryl substituted 4H-3,1-benzoxazin-4-ones and their evaluation as specific inhibitors of the Tissue Factor (TF)/Factor VIIa (FVIIa)-induced pathway of coagulation is reported. Inhibitory activities (IC50 values) in the range 0.17 to > 40 microM
New polymer syntheses, 36. Functionalized aromatic polyethers derived from 4'-substituted 2, 6-difluorobenzophenones.
Kricheldorf HR and Delius U.
Makromol. Chem., 190(6), 1277-1288 (1989)
Regioselective synthesis of 3, 6-disubstituted-2-aminoimidazo [1, 2-a] pyridines.
Jaramillo C, et al.
Tetrahedron Letters, 43(50), 9051-9054 (2002)

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