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240850

Sigma-Aldrich

D -山梨醇

99% (GC)

别名:

D-山梨糖醇

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5 G
$83.20
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$140.00

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预计发货时间2025年4月21日详情

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About This Item

经验公式（希尔记法）:
C6H14O6
CAS号:
50-70-4
分子量:
182.17
Beilstein:
1721899
EC 号:
200-061-5
MDL编号:
MFCD00004708
UNSPSC代码:
12352201
PubChem化学物质编号:
329752554
NACRES:
NA.21

$83.20

预计发货时间2025年4月21日详情

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蒸汽密度

<1 (vs air)

蒸汽压

<0.1 mmHg ( 25 °C)

方案

99% (GC)

表单

powder

旋光性

[α]20/D +104°, c = 0.4 in acidified ammonium molybdate

颜色

white

有效pH范围

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

溶解性

water: soluble 182 g/L at 20 °C (68 °F )

SMILES字符串

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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应用

可用于洗涤原生质球[1]，也可用于等电聚焦，最大限度地减少琼脂糖凝胶中的内渗流。[2]可用于诱导渗胁迫。
山梨醇，一种细菌培养补充剂，已经用于制备选择性平板培养基以培养山梨醇发酵细菌，包括大肠杆菌和小肠结肠炎耶尔森菌的菌株。它也被用作制备免疫电镜用果蝇胚胎的成分之一。[3]它还被用作葡萄糖醛酸木聚糖的添加剂，作为潜在的食品包装材料。[4]

生化/生理作用

山梨醇是一种糖醇，通常用作糖的替代品。它自然产生，也是由葡萄糖合成产生的。食品工业使用山梨醇作为甜味剂、保湿剂、乳化剂、增稠剂或膳食补充剂形式的添加剂。在化妆品、纸张和药品中也发现了山梨醇。自然地，山梨醇通过光合作用广泛存在于植物中，从藻类到蔷薇科的高阶果实。
山梨醇是一种缓慢代谢的糖醇，由葡萄糖还原产生。在多元醇通路中，山梨醇被山梨醇脱氢酶进一步氧化成果糖。山梨醇不容易扩散到细胞膜上，可能会对细胞造成渗透损伤。山梨醇的代谢在糖尿病相关血管并发症的病理学中是最重要的。[5][6]

其他说明

为了全面了解我们针对客户研究提供的各种糖醇产品，建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000436074
0000320535
0000320536
0000320536
SHBS1589

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M Brownlee
Nature, 414(6865), 813-820 (2001-12-14)
Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of myocardial infarction, stroke and limb amputation. Four main molecular mechanisms have been implicated in glucose-mediated vascular damage. All
J Jeffery et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(4), 901-905 (1983-02-01)
A pathway from glucose via sorbitol bypasses the control points of hexokinase and phosphofructokinase in glucose metabolism. It also may produce glycerol, linking the bypass to lipid synthesis. Utilization of this bypass is favored by a plentiful supply of glucose--hence
Shiliang Zhang et al.
Methods in molecular biology (Clifton, N.J.), 475, 275-297 (2008-11-04)
Myoblast fusion in Drosophila has become a powerful genetic system with which to unravel the mechanisms underlying cell fusion. The identification of important components of myoblast fusion by genetic analysis has led to a molecular pathway toward our understanding of
Maria Gröndahl et al.
Biomacromolecules, 5(4), 1528-1535 (2004-07-13)
Free films based on glucuronoxylan isolated from aspen wood were prepared by casting from aqueous solutions and drying in a controlled environment. Addition of xylitol or sorbitol facilitated film formation and thus examination of the material properties of these films.
Isoelectric focusing.
D E Garfin
Methods in enzymology, 182, 459-477 (1990-01-01)
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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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