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Merck

235822

Sigma-Aldrich

间氟苯腈

98%

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About This Item

线性分子式:
FC6H4CN
CAS号:
分子量:
121.11
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

liquid

折射率

n20/D 1.5043 (lit.)

bp

182-183 °C/753 mmHg (lit.)

mp

−16 °C (lit.)

密度

1.133 g/mL at 25 °C (lit.)

SMILES 字串

Fc1cccc(c1)C#N

InChI

1S/C7H4FN/c8-7-3-1-2-6(4-7)5-9/h1-4H

InChI 密鑰

JZTPKAROPNTQQV-UHFFFAOYSA-N

一般說明

Microwave spectrum of 3-fluorobenzonitrile has been studied. Amination of 3-fluorobenzonitrile with morpholine in DMSO at 100°C has been investigated.

應用

3-Fluorobenzonitrile has been used in the preparation of bis(3-cyanophenoxy)phenylenes.

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

154.4 °F - closed cup

閃點(°C)

68 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Microwave spectral study of 3-fluorobenzonitrile.
Dutta A, et al.
Journal of Molecular Spectroscopy, 118(1), 232-236 (1986)
Synthesis of bis (ether nitrile) s and bis (ether acid) s from simplearomatic diols bymeta-fluoro displacement from3-fluorobenzonitrile.
Eastmond GC and Paprotny J.
Journal of Materials Chemistry, 7(8), 1321-1326 (1997)
Xiaotong Cheng et al.
The Journal of clinical investigation, 130(5), 2237-2251 (2020-01-31)
Hypoxia-inducible factor (HIF) is strikingly upregulated in many types of cancer, and there is great interest in applying inhibitors of HIF as anticancer therapeutics. The most advanced of these are small molecules that target the HIF-2 isoform through binding the
Improved yields of meta-amination and symmetrical and unsymmetrical diamination of benzenes.
Brown GR, et al.
Tetrahedron Letters, 42(23), 3917-3919 (2001)
Oriol Planas et al.
Science (New York, N.Y.), 367(6475), 313-317 (2020-01-18)
Bismuth catalysis has traditionally relied on the Lewis acidic properties of the element in a fixed oxidation state. In this paper, we report a series of bismuth complexes that can undergo oxidative addition, reductive elimination, and transmetallation in a manner

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