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Merck

208949

Sigma-Aldrich

2-氟苯乙酸

98%

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About This Item

线性分子式:
FC6H4CH2CO2H
CAS号:
分子量:
154.14
Beilstein:
775955
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

solid

mp

60-62 °C (lit.)

SMILES 字串

OC(=O)Cc1ccccc1F

InChI

1S/C8H7FO2/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4H,5H2,(H,10,11)

InChI 密鑰

RPTRFSADOICSSK-UHFFFAOYSA-N

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一般說明

2-Fluorophenylacetic acid is chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy.

應用

2-Fluorophenylacetic acid was used:
  • in the synthesis of thiazolino[3,2-c]pyrimidin-5,7-diones and N-[2-(3,4-dichlorophenyl)-ethyl]-N′-[2-(2-fluorophenyl)-ethyl]-ethane-1,2-diamine
  • as chiral derivatizing agent for determination of enantiomeric composition of chiral, nonracemic compounds by 19F NMR spectroscopy

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Boron trifluoride-induced reactions of phenylglycidyl ethers: a convenient synthesis of enantiopure, stereodefined fluorohydrins.
Islas-Gonzalez G, et al.
Tetrahedron Letters, 45(33), 6337-6341 (2004)
Joseph Pontillo et al.
Bioorganic & medicinal chemistry letters, 15(5), 1407-1411 (2005-02-17)
Treatment of various 2-methyl oxazolines or thiazolines with chlorocarbonyl isocyanate gives the corresponding bicyclic oxazolino- or thiazolino[3,2-c]pyrimidin-5,7-dione derivatives in very good yield. This reaction has been applied to the rapid syntheses of human gonadotropin-releasing hormone (hGnRH) receptor antagonists for SAR
Yaqun Li et al.
The Korean journal of pain, 34(1), 27-34 (2021-01-01)
Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed the role of prostaglandin D2 (PGD2) signaling in cisplatin-induced neuropathic pain.
Jonathan M Fitzsimmons et al.
Medicinal chemistry, 1(102) (2011-12-25)
Eight halogenated

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