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Merck

17308

Sigma-Aldrich

N,N-二甲基乙酰胺

suitable for peptide synthesis, ≥99.8% (GC)

别名:

DMA, DMAc, Dimethylacetamide

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About This Item

线性分子式:
CH3CON(CH3)2
CAS号:
分子量:
87.12
Beilstein:
1737614
EC號碼:
MDL號碼:
分類程式碼代碼:
12352111
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

3 (vs air)

蒸汽壓力

2 mmHg ( 25 °C)
4 mmHg ( 38 °C)

化驗

≥99.8% (GC)

形狀

liquid

自燃溫度

914 °F

expl. lim.

1.8 %, 100 °F
11.5 %, 160 °F

雜質

≤0.02% water

折射率

n20/D 1.437 (lit.)
n20/D 1.438

pH值

4 (20 °C, 200 g/L)

bp

164.5-166 °C (lit.)

mp

−20 °C (lit.)

密度

0.937 g/mL at 25 °C (lit.)

適合性

in accordance for amine test

應用

peptide synthesis

SMILES 字串

CN(C)C(C)=O

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChI 密鑰

FXHOOIRPVKKKFG-UHFFFAOYSA-N

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應用

N,N-二甲基乙酰胺(DMA)可作为多肽合成溶剂使用。

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

147.2 °F - closed cup

閃點(°C)

64 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Total synthesis of the thiazolyl peptide GE2270 A
Muller HM, et al.
Angewandte Chemie (International Edition in English), 46(25), 4771-4774 (2007)
The Horner-Wadsworth-Emmons reaction in the synthesis of macrocyclic peptides: the Trp-His-Gly-Arg derived macrocycle of moroidin
Harrison JR and Moody CJ
Tetrahedron Letters, 44(28), 5189-5191 (2003)
Peptides derived from nucleoside β-amino acids form an unusual 8-helix
Threlfall R, et al.
Chemical Communications (Cambridge, England), 46(5), 585-587 (2008)
Fen Ran et al.
Acta biomaterialia, 7(9), 3370-3381 (2011-06-11)
An amphiphilic triblock co-polymer of poly(vinyl pyrrolidone)-b-poly(methyl methacrylate)-b-poly(vinyl pyrrolidone) (PVP-b-PMMA-b-PVP) was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The block co-polymer can be directly blended with polyethersulfone (PES) using dimethylacetamide (DMAC) as the solvent to prepare flat sheet and
André H Gröschel et al.
Nature communications, 3, 710-710 (2012-03-20)
Hierarchical self-assembly offers elegant and energy-efficient bottom-up strategies for the structuring of complex materials. For block copolymers, the last decade witnessed great progress in diversifying the structural complexity of solution-based assemblies into multicompartment micelles. However, a general understanding of what

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