推荐产品
應用
- Cyanogen bromide is widely used in protein immobilization and cleavage.
- Under von Braun reaction conditions, CNBr reacts with tertiary amines to yield respective organocyanamides.
- It can also be used to synthesize organic intermediates like cyanuric bromide, derivatives of urea, guanidine, creatine, aryl nitriles, and a variety of heterocyclic compounds.
其他說明
用于选择性断裂肽键（如蛋氨酸）的试剂
訊號詞
Danger
危險分類
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B
安全危害
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
>149.0 °F - closed cup
閃點（°C）
> 65 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Synthesis of hindered chiral guanidine bases starting from (S)-(N, N-dialkyl-aminomethyl) pyrrolidines and BrCN.
Kohn U, et al.
Tetrahedron Asymmetry, 17(5), 811-818 (2006)
Straightforward Conversion of Alcohols into Nitriles.
Tarrade-Matha A, et al.
Synthetic Communications, 40(11), 1646-1649 (2010)
E. Gross
Methods in Enzymology, 11, 238-238 (1967)
R J Simpson et al.
Biochemistry international, 8(6), 787-791 (1984-06-01)
Herein we describe a procedure for the in situ cyanogen bromide cleavage of N-terminally blocked proteins which have been immobilised onto the glass fiber sample disk of the gas-phase sequencer. In this manner, new amino terminii suitable for automated Edman
Cyanogen bromide (CNBr).
Kumar V
Synlett, 2005(10), 1638-1639 (2005)
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