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Merck

146064

Sigma-Aldrich

β-丙氨酸

99%, suitable for ligand binding assays

别名:

β-Ala, 3-氨基丙酸

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国内现货,预计发货时间2025年4月25日详情


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25 G
$98.00
500 G
$106.00
2 KG
$346.00

About This Item

线性分子式:
NH2CH2CH2COOH
CAS号:
分子量:
89.09
Beilstein:
906793
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
39030936
PubChem物質ID:
NACRES:
NA.26

$98.00


国内现货,预计发货时间2025年4月25日详情


获取大包装报价

产品名称

β-丙氨酸, 99%

品質等級

化驗

99%

形狀

powder, crystals or granules

技術

ligand binding assay: suitable

顏色

white

mp

202 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI 密鑰

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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應用

β-丙氨酸被用作MAS孤儿相关受体的配体。[1]它还用于某些酵母菌株的培养基中以检测β-丙氨酸营养缺陷体。[2]

生化/生理作用

内源性 β-氨基酸,是甘氨酸受体的非选择性激动剂和G蛋白偶联孤儿受体TGR7(MrgD)的配体。 β丙氨酸是泛酸的组分。
β丙氨酸是一种 β− 氨基酸,是泛酸的组分,是组氨酰基抗氧化剂二肽肌肽和鹅肌肽生物合成中的限速氨基酸。内源性 β-氨基酸,是甘氨酸受体的非选择性激动剂和G蛋白偶联孤儿受体TGR7(MrgD)的配体。 β-丙氨酸通量通过维持海洋生物、植入前小鼠胚胎和暴露于缺氧应激的哺乳动物细胞的渗透稳定性而发挥细胞保护作用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine.
White WH
The Journal of Biological Chemistry, 276(14), 10794-10800 (2001)
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), a-, and ?-melanocyte stimulating hormone (a-MSH, and ?-MSH), and the conserved core motif HFRW.
N?hr AC, et al.
Neurochemistry International, 102, 105-113 (2017)
Ramin Artang et al.
The American journal of cardiology, 112(12), 1973-1979 (2013-10-01)
Dabigatran has been associated with greater risk of myocardial infarction (MI) than warfarin. It is unknown whether the increased risk is unique to dabigatran, an adverse effect shared by other oral direct thrombin inhibitors (DTIs), or the result of a
Ammar Majeed et al.
Circulation, 128(21), 2325-2332 (2013-10-02)
The aim of this study was to compare the management and prognosis of major bleeding in patients treated with dabigatran or warfarin. Two independent investigators reviewed bleeding reports from 1034 individuals with 1121 major bleeds enrolled in 5 phase III
Robert G Hart et al.
The Canadian journal of cardiology, 29(7 Suppl), S71-S78 (2013-06-29)
Chronic kidney disease (CKD) is prevalent in elderly patients with atrial fibrillation and is an independent risk factor for stroke. Warfarin anticoagulation is efficacious for stroke prevention in atrial fibrillation patients with moderate CKD (stage III, estimated glomerular filtration rate

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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