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Merck

143057

Sigma-Aldrich

Aldrithiol-4

98%

别名:

4,4'-二吡啶基二硫醚, 4,4'-二硫二吡啶

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About This Item

经验公式(希尔记法):
C10H8N2S2
CAS号:
分子量:
220.31
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

solid

mp

76-78 °C (lit.)

溶解度

95% ethanol: soluble 5%, clear, colorless to light yellow

儲存溫度

2-8°C

SMILES 字串

S(Sc1ccncc1)c2ccncc2

InChI

1S/C10H8N2S2/c1-5-11-6-2-9(1)13-14-10-3-7-12-8-4-10/h1-8H

InChI 密鑰

UHBAPGWWRFVTFS-UHFFFAOYSA-N

應用

  • Aldrithiol -4 在一项研究中被用作共底物,通过 体外进化技术 :噬菌体展示 开发出针对甘露糖结合凝集素相关丝氨酸蛋白酶的高度特异性抑制剂。
  • 用于研究在接近生理条件下测定的重组人脑红蛋白和细胞红蛋白的 O2 平衡
  • 用于修饰蛋白研究的金表面

法律資訊

Aldrithiol is a trademark of Sigma-Aldrich Co. LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Leonid S Brown et al.
Journal of molecular biology, 317(3), 471-478 (2002-04-02)
The conformation of the structured EF interhelical loop of bacteriorhodopsin and its change in the M photointermediate were assessed by measuring the rate of reaction of 16 single engineered cysteine residues along the loop with water-soluble sulfhydryl reagents. The exposure
Shwu-Jiuan Sheu et al.
Investigative ophthalmology & visual science, 44(3), 1237-1244 (2003-02-26)
To identify the mechanisms by which oxidative stress with oxidizing agents alters the activity of ion channels in human retinal pigment epithelial (RPE) cells. The effects of oxidizing agents on ion currents were investigated in human RPE R-50 cells with
Nikitas Bistolas et al.
Biochemical and biophysical research communications, 314(3), 810-816 (2004-01-27)
The spectroelectrochemistry of camphor-bound cytochrome P450cam (P450cam) using gold electrodes is described. The electrodes were modified with either 4,4(')-dithiodipyridin or sodium dithionite. Electrolysis of P450cam was carried out when the enzyme was in solution, while at the same time UV-visible
Iveta Imriskova-Sosova et al.
Biochemistry, 44(51), 16949-16956 (2005-12-21)
Members of the Sco protein family are implicated in the assembly of the respiratory complex cytochrome c oxidase. Several possible roles have been proposed for Sco: a copper delivery agent, a site-specific thiol reductase, and an indicator of cellular redox
Soong-Yu Kuo et al.
Archives of toxicology, 77(11), 630-637 (2003-08-21)
The effect of oxidants on Ca(2+) movement in osteoblasts is unclear. In this study, we show that 4,4'-dithiodipyridine (4,4'-DTDP), a reactive disulphide that mobilizes Ca(2+) in muscle, induces an increase in cytoplasmic free-Ca(2+) concentrations ([Ca(2+)](i)) in MG63 human osteosarcoma cells

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