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化驗
98%
折射率
n20/D 1.419 (lit.)
bp
97-100 °C/11 mmHg (lit.)
密度
1.102 g/mL at 25 °C (lit.)
SMILES 字串
CCOCC(O)=O
InChI
1S/C4H8O3/c1-2-7-3-4(5)6/h2-3H2,1H3,(H,5,6)
InChI 密鑰
YZGQDNOIGFBYKF-UHFFFAOYSA-N
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一般說明
Ethoxyacetic acid is biomarker of exposure to widely used industrial chemicals such as alkyl-substituted ethylene glycols and other aliphatic ethers.
應用
Ethoxyacetic acid is metabolite of glycol ether alkoxy acid and was used to evaluate its toxicity in embryonic stem cell test in mouse. It was used in zebrafish embryotoxicity test to study chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis in ovo.
生化／生理作用
Ethoxyacetic acid induces testicular toxicity in rats in vivo .
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
206.6 °F - closed cup
閃點（°C）
97 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
其他客户在看
Esther de Jong et al.
Toxicological sciences : an official journal of the Society of Toxicology, 110(1), 117-124 (2009-04-30)
The embryonic stem cell test (EST) has been proposed as an in vitro assay that might reduce animal experimentation in regulatory developmental toxicology. So far, evaluation of the EST was not performed using compounds within distinct chemical classes. Evaluation within
J Liesivuori et al.
Archives of toxicology, 73(4-5), 229-232 (1999-08-27)
Male Wistar rats were given ethanediol (9.4 g/l), 2-ethoxyethylacetate (5.4 g/l), 2-butoxyethylacetate (2.9 g/l) and 1,2-propanediol (40 g/l) respectively in their drinking water for 2 weeks. Urine was collected during the last 24 h of the exposure. There was a
H Veulemans et al.
British journal of industrial medicine, 50(1), 71-78 (1993-01-01)
A case-control study was conducted among first time patients at a clinic for reproductive disorders. The study group consisted of 1019 cases, defined as patients diagnosed infertile or subfertile on the basis of a spermiogram and 475 controls who were
J C Hoflack et al.
Mutation research, 341(4), 281-287 (1995-02-01)
Ethylene glycol ethers, their aldehyde and their acid metabolites were evaluated for their mutagenicity with the Ames test. The Salmonella typhimurium his- tester strains TA 97a, TA 98, TA 100 and TA 102 were used with and without rat S9
T Sakai et al.
International archives of occupational and environmental health, 64(7), 495-498 (1993-01-01)
In control subjects and workers exposed to glycol ethers and their acetates, we determined the urinary metabolites (three alkoxyacetic acids) by a simple and rapid method. Levels of urinary metabolites were significantly higher in the solvent workers than in the
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