推荐产品
![[（3R）-3-羟基十二酰基]-L-肉碱 analytical standard](/deepweb/assets/sigmaaldrich/product/structures/307/615/dadd9469-b690-4f3b-8106-1471f02b2385/640/dadd9469-b690-4f3b-8106-1471f02b2385.png)
方案
98%
表单
powder
mp
131-134 °C (lit.)
溶解性
acetone: soluble 25 mg/mL, clear, colorless to light yellow
SMILES字符串
CC(=O)CC(=O)Nc1ccc(Cl)cc1
InChI
1S/C10H10ClNO2/c1-7(13)6-10(14)12-9-4-2-8(11)3-5-9/h2-5H,6H2,1H3,(H,12,14)
InChI key
JMRJWEJJUKUBEA-UHFFFAOYSA-N
一般描述
4′-Chloroacetoacetanilide was trilithiated with lithium diisopropylamide and condensed with several aromatic esters, followed by neutralization, separate acid cyclization and rearrangements to yield 4-anilino-6-aryl-2H-pyran-2-ones. It undergoes three-component reaction with a mixture of aromatic aldehyde and 5-aminotetrazole to form N,7-diaryl-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide.
应用
4′-Chloroacetoacetanilide was used in recombinant androgen receptor competitive binding assay for analysis of natural, synthetic and environmental chemicals.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Synthesis and antimicrobial activity of n, 7-diaryl-5-methyl-4, 7-dihydrotetrazolo [1, 5-a] pyrimidine-6-arboxamides.
Gein VL, et al.
Pharmaceutical Chemistry Journal, 44(7), 366-369 (2010)
Preparation of 4-anilino-6-aryl-2 H-pyran-2-ones from trilithiated acetoacetanilides and aromatic esters.
Downs JR, et al.
Canadian Journal of Chemistry, 82(5), 659-664 (2004)
Hong Fang et al.
Chemical research in toxicology, 16(10), 1338-1358 (2003-10-21)
A number of environmental and industrial chemicals are reported to possess androgenic or antiandrogenic activities. These androgenic endocrine disrupting chemicals may disrupt the endocrine system of humans and wildlife by mimicking or antagonizing the functions of natural hormones. The present
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持