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Merck

128635

Sigma-Aldrich

2-羟基乙基甲基丙烯酸酯

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

别名:

HEMA, 乙二醇单甲基丙烯酸酯, 甲基丙烯酸2-羟乙酯

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500 G
$72.40
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$894.00

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500 G
$72.40
1 KG
$85.90
18 KG
$894.00

About This Item

线性分子式:
CH2=C(CH3)COOCH2CH2OH
CAS号:
分子量:
130.14
Beilstein:
1071583
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

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蒸汽密度

5 (vs air)

品質等級

蒸汽壓力

0.01 mmHg ( 25 °C)

化驗

97%

形狀

liquid

包含

≤250 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.453 (lit.)

bp

67 °C/3.5 mmHg (lit.)

密度

1.073 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI 密鑰

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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一般說明

甲基丙烯酸羟乙酯(HEMA)是第一个被用于合成生物医学用水凝胶的单体。通过与更多的亲水单体聚合,可增强HEMA的吸水膨胀性。[1]HEMA在药物发现中被广泛应用。

應用

HEMA被用于合成生物功能性聚(甲基丙烯酸羟乙酯)(PHEMA)共聚物。[2]它还被用于制备用于药物递送的PHEMA光响应膜、[3] 基于HEMA/丙烯酰胺的特殊药物释放水凝胶[1] 以及水溶性HEMA/甲基丙烯酸水凝胶。[4]可研究HEMA对牙髓干细胞迁移(体外)的影响。[5]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

222.8 °F - closed cup

閃點(°C)

106 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.
Giovanna C R M Schver et al.
International journal of pharmaceutics, 581, 119292-119292 (2020-04-04)
The use of water-insoluble carriers for amorphous solid dispersions (ASDs) has attracted more recent interest as the kinetic solubility profiles (KSP) from these systems can achieve a more sustained level of supersaturation when compared with ASDs based on water-soluble polymers.
Thomas J Dursch et al.
Biomaterials, 35(2), 620-629 (2013-10-24)
Two-photon confocal microscopy and back extraction with UV/Vis-absorption spectrophotometry quantify equilibrium partition coefficients, k, for six prototypical drugs in five soft-contact-lens-material hydrogels over a range of water contents from 40 to 92%. Partition coefficients were obtained for acetazolamide, caffeine, hydrocortisone

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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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