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126209

Sigma-Aldrich

2,3-二羟基苯甲酸

99%

别名:

Hypogallic acid, Pyrocatechuic acid

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5 G
$88.00

$88.00

预计发货时间2025年4月21日详情

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5 G
$88.00

About This Item

线性分子式:
(HO)2C6H3CO2H
CAS号:
303-38-8
分子量:
154.12
Beilstein:
2209117
EC 号:
206-139-5
MDL编号:
MFCD00002446
UNSPSC代码:
12352100
PubChem化学物质编号:
24847707
NACRES:
NA.22

$88.00

预计发货时间2025年4月21日详情

获取大包装报价

方案

99%

mp

204-206 °C (lit.)

溶解性

methanol: soluble 50 mg/mL, clear to faintly hazy, orange

官能团

carboxylic acid

SMILES字符串

OC(=O)c1cccc(O)c1O

InChI

1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)

InChI key

GLDQAMYCGOIJDV-UHFFFAOYSA-N

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应用

以 2,3-二羟基苯甲酸为对象，在碱性介质中，用电化学、分光光度法和磁学方法研究了锰与脂肪族和芳香族多羟基配体的配合物 [1]。用于从 创伤弧菌（一种人类病原体 [2]）的低铁培养物中分离新铁载体 vulnibactin。作为共晶形成剂，研究了位置异构对吡拉西坦共晶形成及理化属性的影响 [3]。

生化/生理作用

在大鼠高血容量输注模型中发现 2,3-二羟基苯甲酸是口服有效的铁螯合药物 [4]。其为牛种布氏杆菌 产生的单儿茶酚铁载体 [5]。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
07816BW
00912JD
16616TU
14307HA
14112MX

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3,4-二羟基苯甲酸 analytical standard

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3,4-二羟基苯甲酸

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Nature communications, 9(1), 4647-4647 (2018-11-09)
The emergence of zebrafish Danio rerio as a versatile model organism provides the unique opportunity to monitor the functions of glycosylation throughout vertebrate embryogenesis, providing insights into human diseases caused by glycosylation defects. Using a combination of chemical modifications, enzymatic
N Okujo et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 7(2), 109-116 (1994-04-01)
A new siderophore named vulnibactin has been isolated from low iron cultures of Vibrio vulnificus, a human pathogen. The structure was established as N-[3-(2,3-dihydroxybenzamido)propyl]-1,3-bis[2-(2-hydroxy-phenyl)- trans-5 - methyl-2-oxazoline-4-carboxamido]propane by a combination of acid hydrolysis, nuclear magnetic resonance spectroscopy and positive fast
Xiangmin Liao et al.
Journal of pharmaceutical sciences, 99(1), 246-254 (2009-06-09)
The effect of position isomerism on the co-crystals formation and physicochemical properties was evaluated. Piracetam was used as the model compound. Six position isomers, 2,3-, 2,4-, 2,5-, 2,6-, 3,4-, and 3,5-dihydroxybenzoic acid (DHBA), were used as the co-crystal formers. Co-crystals
The identification of 2, 3-dihydroxybenzoic acid as a potentially useful iron-chelating drug.
J H Graziano et al.
The Journal of pharmacology and experimental therapeutics, 190(3), 570-575 (1974-09-01)
François Le Mauff et al.
The Journal of biological chemistry, 294(28), 10760-10772 (2019-06-07)
During infection, the fungal pathogen Aspergillus fumigatus forms biofilms that enhance its resistance to antimicrobials and host defenses. An integral component of the biofilm matrix is galactosaminogalactan (GAG), a cationic polymer of α-1,4-linked galactose and partially deacetylated N-acetylgalactosamine (GalNAc). Recent
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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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