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Merck

124230

Sigma-Aldrich

溴乙酸叔丁酯

98%

别名:

Bromoacetic acid tert-butyl ester, t-Butyl bromoacetate, tert-Butyl 2-bromoacetate

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10 G
$79.30
50 G
$298.00
250 G
$659.00

About This Item

线性分子式:
BrCH2COOC(CH3)3
CAS号:
分子量:
195.05
Beilstein:
1753010
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

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质量水平

方案

98%

表单

liquid

折射率

n20/D 1.445 (lit.)

沸点

50 °C/10 mmHg (lit.)

密度

1.321 g/mL at 25 °C (lit.)

官能团

bromo
ester

SMILES字符串

CC(C)(C)OC(=O)CBr

InChI

1S/C6H11BrO2/c1-6(2,3)9-5(8)4-7/h4H2,1-3H3

InChI key

BNWCETAHAJSBFG-UHFFFAOYSA-N

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一般描述

溴代乙酸叔丁酯在合成含有 N-连接的乳糖侧链的模型 N-取代的低聚甘氨酸(拟肽)期间用作结构单元[1]

应用

溴乙酸叔丁酯已用于合成:
  • 次氮基三乙酸末端官能化聚苯乙烯(通过原子转移自由基)[2]
  • 用于取代的t-乙酸丁酯的结构单元[3]
  • 二氢吡喃基预交联剂,可用于聚合物辅助的寡聚物的脱保护[4]
  • 胶原酶抑制剂(S,S,R)-(-)- 放线菌素[5] 它是合成 N-草酰甘氨酸衍生物的起始试剂[6]

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

120.2 °F - closed cup

闪点(°C)

49 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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其他客户在看

Slide 1 of 1

1 of 1

Journal of the Chemical Society. Perkin Transactions 1, 459-459 (1993)
SYNTHESIS OF (NITRILOTRIACETIC ACID)-END-FUNCTIONALIZED POLYSTYRENE USING ATOM TRANSFER RADICAL POLYMERIZATION.
Cho HY, et al.
Synthesis, 1000, 4H-4H (2006)
Synthesis of new glycopeptidomimetics based on N-substituted oligoglycine bearing an N-linked lactoside side-chain.
Saha UK and Roy R.
Journal of the Chemical Society. Chemical Communications, 24, 2571-2573 (1995)
Efficient polymer-assisted strategy for the deprotection of protected oligosaccharides.
Hiroshi Tanaka et al.
Angewandte Chemie (International ed. in English), 45(38), 6349-6352 (2006-08-19)
Guillaume Jeannotte et al.
The Journal of organic chemistry, 69(14), 4656-4662 (2004-07-03)
Fused heteroarylprolines were prepared starting from 4-oxo-N-(PhF)proline benzyl ester (6, PhF = 9-(9-phenylfluorenyl)) following two approaches. First, allylation of oxoproline 6 followed by Wacker oxidation gave 1,4-dione 8 that was selectively converted to pyrroloproline 10b, pyrrolopyrrole 12, and pyridazinoproline 9.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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