所有图片(1)
About This Item
经验公式(希尔记法):
C9H8O4
CAS号:
分子量:
180.16
Beilstein:
5742837
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22
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方案
≥97.0% (sum of enantiomers, GC)
表单
solid
旋光性
[α]20/D +83±2°, c = 1.5% in chloroform
光学纯度
enantiomeric ratio: ≥99.0:1.0
mp
96-99 °C
SMILES字符串
OC(=O)[C@H]1COc2ccccc2O1
InChI
1S/C9H8O4/c10-9(11)8-5-12-6-3-1-2-4-7(6)13-8/h1-4,8H,5H2,(H,10,11)/t8-/m1/s1
InChI key
HMBHAQMOBKLWRX-MRVPVSSYSA-N
应用
(R)-1,4-Benzodioxane-2-carboxylic acid is a chiral synthon mostly used in the preparation of doxazosin mesylate, a drug treating benign prostatic hyperplasia.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Characterization of an Indole-3-Acetamide Hydrolase from Alcaligenes faecalis subsp. parafaecalis and Its Application in Efficient Preparation of Both Enantiomers of Chiral Building Block 2, 3-Dihydro-1, 4-Benzodioxin-2-Carboxylic Acid.
Mishra P, et al.
PLoS ONE, 11(7), e0159009-e0159009 (2016)
Elisa Dalla Pozza et al.
International journal of oncology, 46(3), 1099-1108 (2014-12-17)
Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed when metastatic events have occurred. Cancer stem cells (CSCs) play an important role in tumor initiation, metastasis, chemoresistance and relapse. A growing number of studies have suggested that CSCs exist in a dynamic
Chaobin Li et al.
The Plant cell, 32(9), 2823-2841 (2020-07-24)
Zeins are the predominant storage proteins in maize (Zea mays) seeds, while Opaque2 (O2) is a master transcription factor for zein-encoding genes. How the activity of O2 is regulated and responds to external signals is yet largely unknown. Here, we
Maj Sundbom et al.
BMC pharmacology, 8, 3-3 (2008-02-14)
A substantial body of evidence indicates that reduced plasma adiponectin levels may be key in the development of insulin resistance, type 2 diabetes and the metabolic syndrome. Glucocorticoids decrease the levels of adiponectin in animals and humans. Cortisone is transformed
Jinhua Li et al.
EMBO reports, 21(2), e48781-e48781 (2020-01-10)
Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. TGF-β1/Smad3 signalling plays a major pathological role in DN; however, the contribution of Smad4 has not been examined. Smad4 depletion in the kidney using anti-Smad4 locked nucleic acid halted
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