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Merck

114715

Sigma-Aldrich

苯肼 盐酸盐

≥99%

别名:

Phenylhydrazinium chloride

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About This Item

线性分子式:
C6H5NHNH2 · HCl
CAS号:
分子量:
144.60
Beilstein:
3594958
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥99%

形狀

solid

mp

250-254 °C (dec.) (lit.)

溶解度

H2O: soluble 50 mg/mL

SMILES 字串

Cl[H].NNc1ccccc1

InChI

1S/C6H8N2.ClH/c7-8-6-4-2-1-3-5-6;/h1-5,8H,7H2;1H

InChI 密鑰

JOVOSQBPPZZESK-UHFFFAOYSA-N

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應用

盐酸苯肼用于检测贫血小鼠 EPO 反应性正常成红细胞样细胞中 Janus 蛋白酪氨酸激酶 (JAK) 的酪氨酸磷酸化

生化/生理作用

将盐酸苯肼腹腔注射到野生型和 Hp、Hx 单缺失小鼠体内时,会引起急性溶血 ,从而会抑制动物组织切片中辣根过氧化物 (HRP) 残留活性

準備報告

50 g 盐酸苯肼溶于 1 mL 水中,得到澄清、淡黄色溶液。

相關產品

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Phenylhydrazine as inhibitor of horseradish peroxidase for use in immunoperoxidase procedures.
W Straus
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 20(11), 949-951 (1972-11-01)
Clinton Stewart et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 22(1), 612-629 (2019-12-10)
Cyclophosphamide is widely used to treat children with medulloblastoma; however, little is known about its brain penetration. We performed cerebral microdialysis to characterize the brain penetration of cyclophosphamide (130 mg/kg, IP) and its metabolites [4-hydroxy-cyclophosphamide (4OH-CTX) and carboxyethylphosphoramide mustard (CEPM)]
Y Yamamura et al.
Molecular and cellular biology, 18(3), 1172-1180 (1998-03-06)
Abnormal erythropoietin (EPO)-independent cell growth is induced after infection of erythroid progenitor cells with a polycythemic strain of Friend virus (FVp). Binding of its Env-related glycoprotein (gp55) to the EPO receptor (EPOR) mimics the activation of the EPOR with EPO.
Emanuela Tolosano et al.
Blood, 100(12), 4201-4208 (2002-10-24)
Intravascular hemolysis is associated with several pathologic conditions that include hemoglobinopathies, trauma, malaria, and bacterial infections. Among plasma-protective proteins against oxidative damage caused by red blood cell rupture, haptoglobin and hemopexin are thought to play a crucial role. Haptoglobin and
Denham G Cook et al.
The Journal of experimental biology, 214(Pt 17), 2927-2934 (2011-08-13)
The effect of altered oxygen transport potential on behavioural responses to environmental hypoxia was tested experimentally in snapper, Pagrus auratus, treated with a haemolytic agent (phenylhydrazine) or a sham protocol. Standard metabolic rate was not different between anaemic and normocythaemic

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