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Merck

DNASE1

deoxyribonuclease I

别名:
DNL1, DRNI
物种:
UniProtKB ID:
基因ID:
  • Human(1773) Summary: This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13419) deoxyribonuclease I
  • Rat(25633) deoxyribonuclease I
  • naked mole-rat(101713435) deoxyribonuclease I
  • domestic guinea pig(100718441) deoxyribonuclease I
  • sheep(101122154) deoxyribonuclease I
  • Horse(100034219) deoxyribonuclease I
  • cow(282217) deoxyribonuclease I
  • Domestic Rabbit(100009513) deoxyribonuclease I
  • dog(403413) deoxyribonuclease I
  • domestic cat(101096195) deoxyribonuclease I
  • chicken(395725) deoxyribonuclease I
  • Zebrafish(436947) deoxyribonuclease I

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Antibodies

货号
说明
物种反应性
应用
Anti-DNASE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, human, rat
应用
western blot
Anti-DNASE1 (N-terminal) antibody produced in rabbit FITC conjugated, affinity isolated antibody,
物种反应性
bovine, human, rat
应用
Anti-DNASE1 (N-terminal) antibody produced in rabbit HRP conjugated, affinity isolated antibody,
物种反应性
bovine, human, rat
应用

Proteins

货号
说明
物种
脱氧核糖核酸酶 I 来源于牛胰腺, lyophilized powder, Protein ≥85 %, ≥400 Kunitz units/mg protein,
物种
脱氧核糖核酸酶 I 来源于牛胰腺, Type IV, lyophilized powder, ≥2,000 Kunitz units/mg protein,
物种
脱氧核糖核酸酶 I 来源于牛胰腺, Type II-S, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
物种
脱氧核糖核酸酶 I 来源于牛胰腺, Type II, lyophilized powder, Protein ≥80 %, ≥2,000 units/mg protein,
物种
重组DNase I, grade I, from bovine pancreas, expressed in Pichia pastoris,
物种
cow