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Merck

ADRB2

adrenoceptor beta 2, surface

别名:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
物种:
UniProtKB ID:
基因ID:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

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Small Molecule - Agonist

货号
说明
物种
(−)-Isoproterenol hydrochloride, ,
物种
human
克仑特罗 盐酸盐, ≥95%,
物种
human
沙丁胺醇, ,
物种
human
福莫特罗 富马酸酯 二水合物, >98% (HPLC),
物种
human
非诺特罗 氢溴酸盐, ,
物种
human

Small Molecule - Antagonist

货号
说明
物种
ICI 118,551 盐酸盐, ≥98% (HPLC), powder,
物种
human
(±)-普萘洛尔 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
盐酸普萘洛尔, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普萘洛尔 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
马来酸替莫洛尔, United States Pharmacopeia (USP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-β-2 Adrenergic Receptor antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

western blot

Small Molecule - Blocker

货号
说明
物种
索他洛尔 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
索他洛尔 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human
(±)-索他洛尔 盐酸盐, ≥98% (TLC), powder,
物种
human
(S)-(-)-普奈洛尔 盐酸盐, ≥98% (TLC), powder,
物种
human
普罗帕酮 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Adrb2,
物种
mouse
MISSION® esiRNA, targeting human ADRB2,
物种
human