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Merck

ADORA1

adenosine A1 receptor

别名:
RDC7
物种:
UniProtKB ID:
基因ID:
  • Human(134) Summary: The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11539) adenosine A1 receptor
  • Rat(29290) adenosine A1 receptor
  • chicken(374212) adenosine A1 receptor
  • sheep(101109816) adenosine A1 receptor
  • cow(282133) adenosine A1 receptor
  • domestic guinea pig(100135472) adenosine A1 receptor
  • naked mole-rat(101704638) adenosine A1 receptor
  • Zebrafish(100150997) adenosine A1 receptor
  • dog(403961) adenosine A1 receptor
  • domestic cat(101100536) adenosine A1 receptor

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Small Molecule - Agonist

货号
说明
物种
(−)-N6-(2-Phenylisopropyl)adenosine, solid,
物种
human
腺苷, ,
物种
human
间型霉素 A, from Streptomyces kaniharaensis, ≥98% (HPLC),
物种
human
腺苷, United States Pharmacopeia (USP) Reference Standard,
物种
human
腺苷, phyproof® Reference Substance,
物种
human

Small Molecule - Antagonist

货号
说明
物种
虫草素, from Cordyceps militaris,
物种
rat
杀结核菌素, from Streptomyces tubercidicus, ~95%,
物种
rat
8-Cyclopentyl-1,3-dimethylxanthine, ≥98% (HPLC), powder,
物种
human
3-异丁基-1-甲基黄嘌呤, BioUltra, ≥99%,
物种
rat
苏木精, ,
物种
rat

Antibodies

货号
说明
物种反应性
应用
抗腺苷A1受体抗体, Chemicon®, from rabbit,
物种反应性
guinea pig, human, pig, rat, sheep
应用
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-ADORA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-ADORA1 antibody produced in rabbit, ,
物种反应性
human, mouse
应用
immunohistochemistry
western blot
Anti-ADORA1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, rat
应用
ELISA
western blot
Anti-A1 Adenosine Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

货号
说明
物种
尼群地平, >95%, powder,
物种
human, rat
咖啡因, anhydrous, 99%, FCC, FG,
物种
mouse, human, rat
咖啡因, Sigma Reference Standard, vial of 250 mg,
物种
mouse, human, rat
咖啡因, anhydrous, tested according to Ph. Eur.,
物种
mouse, human, rat
咖啡因, meets USP testing specifications, anhydrous,
物种
mouse, human, rat

Small Molecule - Inhibitor

货号
说明
物种
EHNA 盐酸盐, ≥98% (HPLC),
物种
human
Dilazep dihydrochloride, powder,
物种
human
8-(3-Chlorostyryl)caffeine, ≥98% (HPLC), solid,
物种
human, rat, mouse
5′-脱氧-5′-腺苷, ,
物种
human, rat, mouse
α-萘黄酮, ≥98%,
物种
human, rat

Small Molecule - Ligand

货号
说明
物种
2-氯-2′-脱氧腺苷, antileukemic,
物种
rat, human
1,7-二甲基黄嘌呤, ~98%, solid,
物种
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
物种
human, rat
腺苷, ≥99%,
物种
human, rat
茶碱, anhydrous, ≥99%, powder,
物种
mouse, human, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Adora1,
物种
mouse
MISSION® esiRNA, targeting human ADORA1,
物种
human