SML0594

CGP 55845 hydrochloride

≥98% (HPLC)

• Synonym(s): (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydro xypropyl](phenylmethyl)phosphinic acid hydrochloride, CGP 55845A, CGP55845
• Empirical Formula (Hill Notation): C₁₈H₂₂Cl₂NO₃P · HCl
• CAS Number: 149184-22-5
• Molecular Weight: 438.71
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: room temp
• InChI: 1S/C18H22Cl2NO3P/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14/h2-9,13,16,21-22H,10-12H2,1H3,(H,23,24)/t13-,16-/m0/s1
• InChI key: ZODSPDOOCZZEIM-BBRMVZONSA-N

Description

Biochem/physiol Actions

CGP 55845 is a potent selective GABA-B receptor antagonist with an IC₅₀ of 5 nM.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable