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466387

Sigma-Aldrich

Brij® S 100

average Mn ~4,670

Synonym(s):

Polyoxyethylene (100) stearyl ether

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About This Item

Linear Formula:
C18H37(OCH2CH2)nOH, n~100
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
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mol wt

average Mn ~4,670

Quality Level

mp

51-54 °C (lit.)

hydroxyl value

13‑25 mg KOH/g

solubility

propylene glycol and xylene: insoluble

density

1.1 g/mL at 25 °C (lit.)

HLB

18

SMILES string

O(CC[O])CCCCCCCCCCCCCCCCCC

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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Application

Brij® S 100 may be used:
  • as a non-ionic surfactant to study its interactions with luminol electrochemiluminescence for bioanalysis[1]
  • as a carrier material to study the formulation of nimodipine, fenofibrate, and o-vanillin using the particles from gas-saturated solution (PGSS) process[2]
  • as a hydrophilic surfactant in the casting solution to prepare an asymmetric flat sheet nanofiltration membranes and to study its effects on the hydrophilic property of the poly(ethersulfone) (PES) nanofiltration membranes[3]

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Customers Also Viewed

Formulation of nimodipine, fenofibrate, and o-vanillin with Brij S100 and PEG 4000 using the PGSS process
Kravanja G, et al.
Journal of Supercritical Fluids, 135, 245-253 (2018)
J Q Zhang et al.
Drug delivery, 14(6), 381-387 (2007-08-19)
The study describes the development of stealth solid lipid nanoparticles (SLNs) as colloidal carriers for silibinin, a drug with very low solubility. Stealth SLNs were constituted mainly of bioacceptable and biodegradable lipids, such as stearic acid and surfactant Brij 78
S O Williams et al.
Drug development and industrial pharmacy, 26(1), 71-77 (2000-04-01)
The purpose of this study was to scale up an oil/water (o/w) cream formulation containing 40% diethylene glycol monoethyl ether (DGME), developed via 300-g laboratory batches in a 2(5-2) fractional factorial design, to 7-kg batch sizes in a Brogli-10 homogenizer.
Jae-Haeng Song et al.
Drug development and industrial pharmacy, 35(8), 897-903 (2009-02-26)
The oral administration of loratadine, an antihistamine, can have a variety of adverse side effects, such as headache, fatigue, and nausea, because of the transient high blood concentration. To avoid these effects, loratadine can be administered using a transdermal drug
Anne Huhtala et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 19(1), 11-21 (2003-03-22)
This study was undertaken to investigate the use of the in vitro test WST-1, an assay of cell proliferation and viability, for a preliminary safety evaluation of topical ophthalmic preparations. The cytotoxicity of two surfactants, benzalkonium chloride (BAC) and polyoxyethylene-20-stearyl

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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