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About This Item
Empirical Formula (Hill Notation):
C11H15N5O5
CAS Number:
Molecular Weight:
297.27
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Recommended Products
Assay
~95%
form
solid
storage temp.
−20°C
SMILES string
CNC1=NC(=O)c2ncn(C3OC(CO)C(O)C3O)c2N1
InChI
1S/C11H15N5O5/c1-12-11-14-8-5(9(20)15-11)13-3-16(8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15,20)
InChI key
SLEHROROQDYRAW-UHFFFAOYSA-N
Application
N2-Methylguanosine (m2is used to characterize and study the metabolism of naturally occurring methylated guanosine in RNAs.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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H A Heus et al.
European journal of biochemistry, 188(2), 275-281 (1990-03-10)
The 3'-terminal colicin fragments of 16S ribosomal RNA were isolated from Bacillus stearothermophilus and from its kasugamycin-resistant (ksgA) derivative lacking N6-dimethylation of the two adjacent adenosines in a hairpin loop. The fragment from the ksgA strain still contains a naturally
Quiping Cao et al.
RNA (New York, N.Y.), 16(1), 221-227 (2009-11-26)
Pumilio 2 (Pum2) interacts with the 3' UTR-containing pumilio binding element (PBE) of RINGO/SPY mRNA to repress translation in Xenopus oocytes. Here, we show that Pum2 also binds directly to the 5' 7mG cap structure; in so doing, it precludes
Hua-Yu Li et al.
Journal of mass spectrometry : JMS, 44(5), 641-651 (2009-01-15)
Urinary-modified nucleosides have a potential role as cancer biomarkers for a number of malignant diseases. High performance liquid chromatography (HPLC) was combined with full-scan mass spectrometry, MS/MS analysis and accurate mass measurements in order to identify purine nucleosides purified from
Joanna Kowalska et al.
RNA (New York, N.Y.), 14(6), 1119-1131 (2008-04-24)
Analogs of the mRNA cap are widely employed to study processes involved in mRNA metabolism as well as being useful in biotechnology and medicinal applications. Here we describe synthesis of six dinucleotide cap analogs bearing a single phosphorothioate modification at
Victoria H Cowling
The Biochemical journal, 425(2), 295-302 (2009-12-23)
The 7-methylguanosine cap added to the 5' end of mRNA is essential for efficient gene expression and cell viability. Methylation of the guanosine cap is necessary for the translation of most cellular mRNAs in all eukaryotic organisms in which it
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