Skip to Content
Merck
All Photos(1)

Documents

B1557

Sigma-Aldrich

Hyaluronan biotin sodium salt

≥97%, soluble powder

Synonym(s):

Hyaluronic acid biotin

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD03457192
UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

100

Assay

≥97%

form

soluble powder

mol wt

≥700 kDa

loss

≤5% loss on drying

color

white to tan

storage temp.

2-8°C

Related Categories

Application

Hyaluronan biotin (HA-biotin) may be used as a specific bioaffinity probe to detect HA-binding proteins (hyaladherins), HA-receptors and HA-binding components in tissues and cells. Hyaluronan biotin may be used in the development of affinity binding systems for the immobilization and purification of hyaladherins. HA-biotin may be used in hydrogel development and for drug targeting.
Highly sensitive probe for detecting nanogram levels of hyaluronan binding proteins (hyaladherins).

Other Notes

From cocks comb or fermentation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

D Liu et al.
Frontiers in bioscience : a journal and virtual library, 3, d631-d636 (1998-06-23)
CD44 is a cell surface glycoprotein present on many cell types. Many CD44 isoforms have been identified. All CD44 isoforms utilize identical transmembrane and cytoplasmic domains. The hematopoietic form of CD44 (CD44H) is the major CD44 protein present on normal
T Pouyani et al.
Bioconjugate chemistry, 5(4), 370-372 (1994-07-01)
Hyaluronic acid (HA) is a linear polysaccharide composed of repeating disaccharide units of D-glucuronic acid (GlcUA) and N-acetyl-D-glucosamine (GlcNAc). Hyaluronate plays an important role in many biological processes as mediated by its interactions with a number of HA-binding proteins (the
P Auvinen et al.
The American journal of pathology, 156(2), 529-536 (2000-02-10)
Hyaluronan (HA) is an extracellular matrix polysaccharide that promotes cell migration through its cell surface receptors and by effecting changes in the physical environment. HA expression is frequently increased in malignant tumors, whereas its association with the invasive potential and
Keiko Hasegawa et al.
The Journal of investigative dermatology, 127(7), 1657-1663 (2007-03-17)
Versican interacts with hyaluronan (HA) at its N-terminus and with fibrillin-1 at its C terminus. As versican in the dermis connects microfibrils to the HA-rich matrix for viscoelasticity, dermal diseases may involve destruction of these complexes. A recombinant versican protein
Yuan Cui et al.
Applied biochemistry and biotechnology, 169(1), 239-249 (2012-11-28)
Hyaluronic acid is a naturally ionic polysaccharide with cancer cell selectivity. It is an ideal candidate material for delivery of anticancer agents. In this study, hyaluronic acid (HA) micro-hydrogel loaded with anticancer drugs was prepared by the biotin-avidin system approach.
View All Related Papers

Articles

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service