390704

(2-Hydroxypropyl)-γ-cyclodextrin

extent of labeling: 0.6 molar substitution

• Sinónimos: HP-γ-CD, HPGCD, HGC
• Número de CAS: 128446-34-4
• Número MDL: MFCD16621721
• Código UNSPSC: 12352201
• NACRES: NA.22

Propiedades

• Formulario: powder
• Nivel de calidad: 100
• actividad óptica: [α]20/D +145°, c = 1 in H₂O
• mol peso: average M_w ~1,580
• Extensión del etiquetado: 0.6 molar substitution
• cadena SMILES: O1[C@@H]2O[C@H]([C@H](O[C@@H]3O[C@H]([C@H](O[C@@H]4O[C@H]([C@H](O[C@@H]5O[C@H]([C@H](O[C@@H]6O[C@H]([C@H](O[C@@H]7O[C@H]([C@H](O[C@@H]8O[C@H]([C@H]1[C@H]([C@@H]8O)O)COCC(O)C)[C@H]([C@@H]7O)O)CO)[C@H]([C@@H]6O)O)COCC(O)C)[C@H]([C@@H]5O)O)CO)[C@H]([C@@H]4O)
• InChI: 1S/C51H88O38/c1-14(56)8-73-11-21-42-29(64)36(71)50(81-21)85-40-19(6-54)79-48(34(69)27(40)62)89-44-23(13-75-10-16(3)58)82-51(37(72)30(44)65)86-41-20(7-55)78-47(33(68)26(41)61)88-43-22(12-74-9-15(2)57)80-49(35(70)28(43)63)84-39-18(5-53)76-45(31(66)24(39)59)83-38-17(4-52)77-46(87-42)32(67)25(38)60/h14-72H,4-13H2,1-3H3/t14?,15?,16?,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-/m0/s1
• Clave InChI: ODLHGICHYURWBS-RYJYQAAZSA-N

Descripción

Descripción general

(2-Hydroxypropyl)-γ-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.

Aplicación

(2-Hydroxypropyl)-γ-cyclodextrin may be used:

• As a mobile phase additive in the study of the host-guest interaction with organic low molecular mass compounds prior to their quantification using reversed phase-high performance liquid chromatography (RP-HPLC) technique.
• As a chiral surfactant for the analysis of econazole by micellar electrokinetic chromatography (MEKC).
• As an analytical standard for the determination of the analyte in biological samples by HPLC.
• As a chiral selector for the identification of propiconazole by MEKC.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)