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M4542

Sigma-Aldrich

Melanin Concentrating Hormone rat

≥90% (HPLC)

Synonym(s):

MCH

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About This Item

Empirical Formula (Hill Notation):
C105H160N30O26S4
CAS Number:
128315-56-0
Molecular Weight:
2386.84
MDL number:
MFCD00080193
UNSPSC Code:
51111800
PubChem Substance ID:
329817901
NACRES:
NA.32

biological source

synthetic (organic)

assay

≥90% (HPLC)

form

powder

composition

Peptide content, ≥70%

solubility

water: 1 mg/mL, clear, colorless

UniProt accession no.

P14200

shipped in

ambient

storage temp.

−20°C

SMILES string

CSCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CC(C)C)NC1=O)C(C)C)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc6ccccc6)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C105H160N30O26S4/c1-53(2)42-70-86(144)118-50-80(138)119-64(24-16-36-114-103(108)109)90(148)133-83(55(5)6)100(158)130-73(45-58-28-30-60(136)31-29-58)93(151)124-69(26-18-38-116-105(112)113)101(159)135-39-19-27-78(135)99(157)132-77(98(156)128-74(46-59-49-117-63-23-15-14-22-61(59)63)95(153)121-66(32-33-79(107)137)91(149)134-84(56(7)8)102(160)161)52-165-164-51-76(97(155)123-68(35-41-163-10)88(146)126-70)131-87(145)65(25-17-37-115-104(110)111)120-92(150)71(43-54(3)4)127-89(147)67(34-40-162-9)122-96(154)75(48-82(141)142)129-94(152)72(44-57-20-12-11-13-21-57)125-85(143)62(106)47-81(139)140/h11-15,20-23,28-31,49,53-56,62,64-78,83-84,117,136H,16-19,24-27,32-48,50-52,106H2,1-10H3,(H2,107,137)(H,118,144)(H,119,138)(H,120,150)(H,121,153)(H,122,154)(H,123,155)(H,124,151)(H,125,143)(H,126,146)(H,127,147)(H,128,156)(H,129,152)(H,130,158)(H,131,145)(H,132,157)(H,133,148)(H,134,149)(H,139,140)(H,141,142)(H,160,161)(H4,108,109,114)(H4,110,111,115)(H4,112,113,116)/t62-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-/m0/s1

InChI key

MWLPXSMFEPHETN-QRXCLJFASA-N

Gene Information

rat ... Pmch(24659)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Chengquan Wang et al.
The Analyst, 144(16), 4772-4780 (2019-07-04)
In recent years, a ratiometric electrochemical method has been investigated due to its ability to effectively reduce the background electrical signals via the introduction of an internal calibration mechanism, which has great practical significance in the detection of mycotoxins in
M Rossi et al.
Brain research, 846(2), 164-170 (1999-11-11)
Melanin concentrating hormone (MCH) is recognised as a hypothalamic appetite stimulant. The mechanism of action of MCH is undetermined largely due to lack of identification of hypothalamic MCH receptors. We designed in vivo and in vitro studies to further characterise
Chu Hongxia et al.
Mikrochimica acta, 186(4), 242-242 (2019-03-17)
Graphene quantum dots (GQDs) were prepared via pyrolysis of citric acid and glutamic acid, then reacted with chlorauric acid to form a gold/graphene quantum dot hybrid (Au/GQD), and finally connected with hairpin DNA probe 1 (H1) and thionine (Thi). The H1-Au/GQD-Thi
Melanin-concentrating hormone facilitates migration of preadipocytes.
Cook LB
Molecular and Cellular Endocrinology (2010)
Melanin-concentrating hormone functions in the nervous system: food intake and stress.
Hervieu G
Expert Opinion on Therapeutic Targets (2003)
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