31224

Chloramine T trihydrate

reag. Ph. Eur., 98.0-103.0%

• Synonym(s): N-Chloro-p-toluenesulfonamide sodium salt
• Linear Formula: CH₃C₆H₄SO₂NClNa · 3H₂O
• CAS Number: 7080-50-4
• Molecular Weight: 281.69
• Beilstein/REAXYS Number: 3924168
• EC Number: 204-854-7
• MDL number: MFCD00149066
• UNSPSC Code: 12352100
• PubChem Substance ID: 57648517
• NACRES: NA.21

Properties

• agency: USP/NF; reag. Ph. Eur.
• Quality Level: 100
• assay: 98.0-103.0%
• impurities: ≤1.5% insoluble in ethanol
• pH: 8-10 (20 °C, 5%)
• mp: 167-170 °C (lit.)
• SMILES string: O.O.O.Cc1ccc(cc1)S(=O)(=O)N([Na])Cl
• InChI: 1S/C7H7ClNO2S.Na.3H2O/c1-6-2-4-7(5-3-6)12(10,11)9-8;;;;/h2-5H,1H3;;3*1H2/q-1;+1;;;
• InChI key: NZYOAGBNMCVQIV-UHFFFAOYSA-N

Description

General description

Chloramine-T trihydrate is a widely used oxidizing agent in organic synthesis. It acts as a source of halonium cation and nitrogen anion and thus acts as a base and nucleophile. Due to its reactivity with a wide range of functional groups, it is involved in different molecular transformations. It is effective in acidic, neutral, and basic conditions[1].

Application

Chloramine-T trihydrate can be used as:

• A reagent for chlorination in drinking water treatment[1].
• A dehydrogenating agent for the oxidative dehydrogenation of aromatic aldehyde phenylhydrazones to synthesize nitrile imines[2].
• The nitrene source for the aziridination of alkenes and the amidation of cyclic ethers[3].

Safety Information

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314,H334
• pcodes: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B
• supp_hazards: EUH031
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 2
• flash_point_f: 377.6 °F - closed cup
• flash_point_c: 192 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges