524731

Phosphodiesterase 4A4, His•Tag^®, Human, Recombinant, S. frugiperda

• Synonym(s): PDE4A4, cAMP-specific phosphodiesterase 4A isoform 4
• UNSPSC Code: 12352202

Properties

• recombinant: expressed in insect cells (S. frugiperda)
• Quality Level: 100
• form: liquid
• specific activity: ≥0.5 U/μL
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Full-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminus to a His•Tag sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.

Full-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminuse to a His•Tag sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.

Warning

Toxicity: Standard Handling (A)

Unit Definition

One unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5.

Physical form

In 150 mM NaCl, 10 mM Tris-HCl, pH 8.3.

Other Notes

Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol.538, 39.
Xu, R.X., et al. 2000. Science288, 1822.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable