1.04163

Sodium chloride

granulated, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP

• Synonym(s): Halite, NaCl
• Linear Formula: NaCl
• CAS Number: 7647-14-5
• Molecular Weight: 58.44
• Beilstein/REAXYS Number: 3534976
• MDL number: MFCD00003477
• UNSPSC Code: 12352302

Properties

• grade: GMO free; Halal; Kosher
• Quality Level: 500
• agency: BP; ChP; JP; Ph. Eur.; USP
• product line: EMPROVE^® EXPERT
• form: granular
• mp: 801 °C (lit.)
• application(s): liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical; solid formulation
• storage temp.: 2-30°C
• SMILES string: [Na+].[Cl-]
• InChI: 1S/ClH.Na/h1H;/q;+1/p-1
• InChI key: FAPWRFPIFSIZLT-UHFFFAOYSA-M

Description

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, Sodium chloride granulated is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium chloride is a mineral salt with broad range of applications in pharmaceutical formulations. It is typically used as an osmotic agent in liquid dosage forms e.g. for preparation of isotonic formulations, as bulking or coating agent for solid dosage forms, as well as for semi-solid dosage forms like creams.
Due to its low microbial and endotoxin limits, Sodium chloride granulated Emprove^® Expert is especially suitable for high-risk applications.

Packaging

1.04163.0001 / 3x1kg / PE Bottle
1.04163.1000 / 1kg / PE Bottle
1.04163.9026 / 25kg / PE Bag in PE Drum
1.04163.9500 / 500kg / Big Bag

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable