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880138P

Avanti

DSPE-PEG(2000) Carboxy NHS

Avanti Research - A Croda Brand

Synonym(s):

DSPE-PEG(2000) Carboxy NHS, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000, NHS ester] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C135H260N2NaO57P
CAS Number:
Molecular Weight:
2877.45
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

package of 1 × 10 mg

manufacturer/tradename

Avanti Research - A Croda Brand

application(s)

advanced drug delivery

lipid type

polymerizable lipids

shipped in

dry ice

storage temp.

−20°C

application


  • Enhanced detection of myeloma cells: DSPE-PEG(2000) Carboxy was used to create fluorescence labeled XT5 modified nano-capsules, enhancing the sensitivity of detecting myeloma cells. This application demonstrates its potential in biomedical diagnostics and targeted therapy (Norouz Dizaji et al., 2022).

  • Improving drug encapsulation efficiency: The use of DSPE-PEG(2000) Carboxy in pre-formed liposomes for drug delivery showcases a method that significantly improves carboplatin encapsulation, highlighting its role in optimizing chemotherapeutic drug formulations (Wehbe et al., 2017).

  • Targeted drug delivery for cardiovascular diseases: DSPE-PEG(2000) Carboxy was integral in the development of PEGylated-nanoliposomal formulations of clusterin, aimed at treating amyloidogenic light chain-induced endothelial dysfunction, underscoring its utility in targeted cardiovascular therapies (Guzman-Villanueva et al., 2018).

Packaging

5 mL Amber Glass Screw Cap Vial (880138P-25MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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