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A21401

Sigma-Aldrich

4-Acetylpyridine

97%

Synonym(s):

Methyl 4-pyridyl ketone

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About This Item

Empirical Formula (Hill Notation):
C7H7NO
CAS Number:
1122-54-9
Molecular Weight:
121.14
Beilstein/REAXYS Number:
107629
EC Number:
214-350-9
MDL number:
MFCD00006433
UNSPSC Code:
12352100
PubChem Substance ID:
24890629
NACRES:
NA.22

assay

97%

form

liquid

refractive index

n20/D 1.529 (lit.)

SMILES string

CC(=O)c1ccncc1

InChI

1S/C7H7NO/c1-6(9)7-2-4-8-5-3-7/h2-5H,1H3

InChI key

WMQUKDQWMMOHSA-UHFFFAOYSA-N

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Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Y Imamura et al.
Journal of biochemistry, 125(1), 41-47 (1999-01-09)
An enzyme responsible for the ketone-reduction of 4-benzoylpyridine (4BP) was purified 350-fold to homogeneity from the cytosolic fraction of rabbit heart. The purified enzyme exhibited a molecular mass of 110 kDa on gel filtration, and 27 kDa on SDS-PAGE, indicating
Y Imamura et al.
Biochemistry and molecular biology international, 33(5), 893-899 (1994-08-01)
A correlation was observed between the values of specificity constant (kcat/Km) of carbonyl reductase from rabbit liver for acetohexamide analogs and their partition coefficients. This result indicates that the hydrophobicity in straight-chain alkyl groups of acetohexamide analogs plays an important
S G Zhu et al.
Brain research, 481(2), 356-360 (1989-03-06)
Measurements of striatal choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities indicated that systemic administration of 4-8 mg/kg of MK-801 to rats completely blocked neuronal damage due to intrastriatal injections of 75-150 nmol of quinolinic acid. Similar experiments with
Y Imamura et al.
Biochemistry and molecular biology international, 31(6), 1105-1110 (1993-12-01)
Carbonyl reductase from rabbit kidney was rapidly inactivated by diethylpyrocarbonate (DEPC). A similar inactivation was observed in photooxidation of the enzyme by methylene blue. The inactivation by DEPC was time- and concentration-dependent and followed pseudo-first-order kinetics. The results obtained from
A Hall et al.
Neuroscience letters, 85(1), 110-112 (1988-02-15)
4-Acetylpyridine, earlier reported by us to be an anticonvulsant, offers long-lasting protection after a single administration against hypothermic restraint stress-induced gastric ulceration in mice. Electroshock convulsions, marginally but not significantly protective against such ulcers themselves, when coupled with 4-acetylpyridine administration
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