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915580

Sigma-Aldrich

Bioactive glass

powder, S53P4, ≥98%, 50-250 μm particle size

Synonym(s):

Bioglass ceramics, Silica glass

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About This Item

Linear Formula:
CaO:SiO2:P2O5
UNSPSC Code:
12352103
NACRES:
NA.23

Quality Level

assay

≥98%

form

powder

particle size

50-250 μm

Application

Bioactive glass is able to form a hydroxyapatite-like surface layer thus providing a stable bond to bone cells. In addition, bioactive glass has been shown to stimulate bone cells regeneration. Due to its biocompatability and osteogenic capacity applications include tissue engineering, enamel reconstruction, bio-coatings, and high temperature adhesives. Furthermore, S53P4 has displayed antimicrobial activity.

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Danger

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B - STOT RE 2 Inhalation - STOT SE 3

target_organs

Lungs, Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3


Certificates of Analysis (COA)

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Lorenzo Drago et al.
Materials (Basel, Switzerland), 11(2) (2018-03-03)
Bone defects caused by trauma or pathological events are major clinical and socioeconomic burdens. Thus, the efforts of regenerative medicine have been focused on the development of non-biodegradable materials resembling bone features. Consequently, the use of bioactive glass as a
Francesco Baino et al.
Journal of functional biomaterials, 9(1) (2018-03-23)
Bioactive glasses caused a revolution in healthcare and paved the way for modern biomaterial-driven regenerative medicine. The first 45S5 glass composition, invented by Larry Hench fifty years ago, was able to bond to living bone and to stimulate osteogenesis through
Julian R Jones
Acta biomaterialia, 9(1), 4457-4486 (2012-08-28)
Bioactive glasses are reported to be able to stimulate more bone regeneration than other bioactive ceramics but they lag behind other bioactive ceramics in terms of commercial success. Bioactive glass has not yet reached its potential but research activity is

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