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Sigma-Aldrich

TentaGel™ S-NH2

extent of labeling: 0.20-0.35 mmol/g N loading

Synonym(s):

O-(2-Aminoethyl)polyethylene glycol polymer-bound

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About This Item

MDL number:
MFCD00217899
UNSPSC Code:
12352116
PubChem Substance ID:
24888602
NACRES:
NA.22

product line

TentaGel™

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

extent of labeling

0.20-0.35 mmol/g N loading

particle size

110-150 μm

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

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Application

TentaGel™ S-NH2 can be used:
  • As a support in the synthesis of L-Leu based peptides and oligomers, which are used as catalysts in Julia-Colonna epoxidation of chalcones.
  • In the synthesis of 1,3-dialkyl quinazoline-2,4-diones.
  • To synthesize N-substituted amidinoaryloxypyridine analogs as potent factor Xa inhibitors.

Legal Information

TentaGel is a trademark of Rapp Polymere GmbH

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Highly enantioselective enone epoxidation catalyzed by short solid phase-bound peptides: dominant role of peptide helicity
Berkessel A, et al.
Organic Letters, 3(24), 3839-3842 (2001)
Solid-phase synthesis of 1, 3-dialkyl quinazoline-2, 4-diones
Buckman BO and Mohan R
Tetrahedron Letters, 37(26), 4439-4442 (1996)
Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor Xa inhibitors
Mohan R, et al.
Bioorganic & Medicinal Chemistry Letters, 8(14), 1877-1882 (1998)

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