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Sigma-Aldrich

HEPES

Synonym(s):

4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid

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About This Item

UNSPSC Code:
12352200

form

chunks

solubility

water: 0.5 g/mL, clear, colorless

Application

Buffer useful in the physiological pH range.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The Journal of Organic Chemistry, 58, 2663-2663 (1993)
Aldrichimica Acta, 16, 35-35 (1983)
M Vasseur et al.
The American journal of physiology, 264(1 Pt 1), C27-C31 (1993-01-01)
The fluorescence intensity of 6-methoxy-N-(3-sulfopropyl)quinolinium (SPQ) in an N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES) 2-(N-morpholino)ethanesulfonic acid (MES)-Tris(hydroxymethyl)aminomethane buffer, pH 7.0, decreased as a function of Cl- concentration and/or gluconate concentration, as expected. Contrary to expectation, however, the fluorescence intensity progressively increased as the
Sunbae Lee et al.
PloS one, 6(4), e18594-e18594 (2011-04-16)
The mechanisms by which MAP kinases recognize and phosphorylate substrates are not completely understood. Efforts to understand the mechanisms have been compromised by the lack of MAPK-substrate structures. While MAPK-substrate docking is well established as a viable mechanism for bringing
Yun Ho Choi et al.
Anatomy & cell biology, 43(4), 317-324 (2011-01-27)
Alpha-lipoic acid (LA), a naturally occurring dithiol compound, is an essential cofactor in metabolic reactions involved in energy utilization. LA improves glycemic control, reduces diabetic polyneuropathies, atherosclerosis, and allergic inflammation. The effects of LA on mast cell-mediated anaphylactic reactions, however

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