Syringe Filters for Chromatography

We carry both Millex^® and Whatman^® syringe filters, the two premier brands in syringe filters for chromatography. Our combined portfolio offers many different membranes and housings for use in a wide range of applications.

Syringe Filter Selection Guide for Chromatography

The presence of particles in chromatography samples can cause pressure build up in the system, leading to instrument shutdown. This is especially true in UHPLC, due to its small particle-packed columns and narrow bore tubing. Regardless of the application, this potential problem is easily eliminated by sample filtration.

Application	HPLC	UPLC®/UHPLC	Ion Chromatography/IC
Recommended Pore Size	0.45 μm syringe filter	0.2 μm syringe filter	0.45 μm or 0.2 μm syringe filters
Recommend Diameter by Sample Volume	<1 mL: 4 mm 1-10 mL: 13 mm 10-100 mL: 30-33	<1 mL: 4 mm 1-10 mL: 13 mm 10-100 mL: 30-33 mm	1-10 mL: 13 mm 10-100 mL: 25 mm
Chemical Compatibility	Broad chemical compatibility (aqueous and organic)	Broad chemical compatibility (aqueous and organic)	Broad chemical compatibility (aqueous)
Extractables	Low extractables prevent sample contamination	Low extractables prevent sample contamination	Low levels of ionic extractables prevent sample contamination
	View recommended syringe filters for HPLC	View recommended syringe filters for UHPLC	View recommended syringe filters for IC

Recommended Products by Application

Syringe Filters for HPLC

Sample volume	Membrane Type	Product Description	Product Number
<1 mL	PTFE, hydrophilic	Millex®-LCR 0.45µm hydrophilic PTFE syringe filter, 4mm	SLLHR04NL
1-10 mL	PTFE, hydrophilic	Millex®-LCR 0.45µm hydrophilic PTFE syringe filter, 13mm	SLCRX13
	Regenerated Cellulose	Whatman Spartan® HPLC certified syringe filters, 13mm	WHA10463110
10-100 mL
	PTFE, hydrophilic	Millex®-LCR 0.45µm hydrophilic PTFE syringe filter, 33mm	SLCR033
	Regenerated Cellulose	Whatman Spartan® HPLC certified syringe filters, 30mm	WHA10463053

Syringe Filters for UPLC^® / UHPLC

Sample volume	Membrane Type	Product Description	Product Number
<1 mL	PTFE, hydrophilic	Millex®-LG 0.20µm hydrophilic PTFE syringe filter, 4mm	SLLGR04NL
1-10 mL	PTFE, hydrophilic	Millex®-LG 0.20µm hydrophilic PTFE syringe filter, 13mm	SLLGX13
	Regenerated Cellulose	Whatman Spartan® HPLC certified syringe filters, 13mm	WHA10463100
10-100 mL
	PTFE, hydrophilic	Millex®-LCR 0.20µm hydrophilic PTFE syringe filter, 33mm	SLLG033
	Regenerated Cellulose	Whatman Spartan® HPLC certified syringe filters, 30mm	WHA10463060

Syringe Filters for Ion Chromatography/IC

Sample volume	Membrane Type	Product Description	Product Number
1-10 mL	PTFE, hydrophilic	Millex®-LH 0.45µm hydrophilic PTFE syringe filter, 13mm	SLLHC13NL
	PTFE, hydrophilic	Millex®-LH 0.20µm hydrophilic PTFE syringe filter, 13mm	SLLGC13NL
	Anopore®	Whatman Anotop® IC and LC syringe filter, Anotop® 10 IC Syringe Filter, pore size 0.2 μm, polypropylene housing,	WHA68099233
10-100 mL	PTFE, hydrophilic	Millex®-LH 0.45µm hydrophilic PTFE syringe filter, 25mm	SLLHC25NS
	PTFE, hydrophilic	Millex®-LH 0.20µm hydrophilic PTFE syringe filter, 25mm	SLLGC25NS
	Anopore®	Whatman Anotop® IC and LC syringe filter, Anotop® 25 LC Syringe Filter, pore size 0.2 μm, polypropylene housing,	WHA20025100