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Merck

Synthesis and in vitro antibacterial properties of 2-(3-bromo-5-isoxazolylideneamino-oxy)acetamido-beta-lactam derivatives.

Farmaco (Societa chimica italiana : 1989) (1991-07-01)
A Sala, D Chiarino, M Napoletano, E Albini, A Carenzi
ABSTRAKT

The synthesis of new 2-(3-bromo-5-isoxazolylideneamino-oxy)acetic acids and their condensation derivatives with suitable beta-lactam nuclei is reported. Their antibacterial properties have been tested in vitro. An interesting activity against Gram-positive bacteria including beta-lactamase-producing microorganisms was found among the cephalosporanic acid derivatives.

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Sigma-Aldrich
O-(Carboxymethyl)hydroxylamine hemihydrochloride, 98%