[Interspecific differences in kemantan pharmacokinetics].

[Interspecific differences in kemantan pharmacokinetics].

Eksperimental'naia i klinicheskaia farmakologiia (1994-11-01)

S S Boĭko, V P Zherdev, N A Kisliak, B M Piatin, N V Klimova, P V Glan, A A Dvorianinov

ABSTRAKT

The pharmacokinetics of the new immunostimulant kemantane, adamantane derivative, used in two species of animals (rats and rabbits) and man was studied. There were significant differences in the pharmacokinetics of kemantane and its active metabolite--adamantane-1,4-diol between the species.