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Merck

Efficacy of ceftibuten for pediatric patients undergoing adenotonsillectomy.

Boletin de la Asociacion Medica de Puerto Rico (2003-11-19)
C Juarbe
ABSTRAKT

A survey between Otolaryngologist Head and Neck Surgeons in Puerto Rico and a prospective study was done, to evaluate the efficacy of ceftibuten in pediatric patients undergoing adenotonsillectomy. Surgery of the tonsils and adenoids is the most common operation performed in the pediatric age by the Otolaryngologist Head and Neck Surgeons in Puerto Rico. Over 70% are performed in a ambulatory setting and almost all of the patients are given antibiotics after surgery. Ceftibuten was given to 112 pediatrics patients after surgery. Adenotonsillectomy is a painful operation and children do not take medication well after surgery. One of the benefits of this third generation cephalosporin, is that is given once a day. Twenty events were reported taking the medication, but only seven patients had to discontinue its use. Ceftibuten had a tolerance rate of 94%. Ceftibuten seems to be a safe antibiotic to use in pediatric patients undergoing adenotonsillectomy and has the convenience of being given once a day.

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Sigma-Aldrich
Ceftibuten hydrate, ≥98% (HPLC)