- Synthesis and evaluation of a tri-tyrosine decorated dextran MR contrast agent for vulnerable plaque detection.
Synthesis and evaluation of a tri-tyrosine decorated dextran MR contrast agent for vulnerable plaque detection.
Chemical communications (Cambridge, England) (2011-04-02)
Anne Beilvert, Roger Vassy, Emmanuelle Canet-Soulas, Olivier Rousseaux, Luc Picton, Didier Letourneur, Frédéric Chaubet
PMID21455511
ABSTRAKT
This communication reports the synthesis, characterization and in vivo evaluation in mice of a new tri-tyrosine conjugated MR contrast agent, which may help to identify vulnerable plaques in atherosclerosis by targeting the lipid core.