1502508

Penicylina G potasowa

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Penicillin G potassium salt, Benzylpenicillin potassium salt
• Wzór empiryczny (zapis Hilla): C₁₆H₁₇KN₂O₄S
• Numer CAS: 113-98-4
• Masa cząsteczkowa: 372.48
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750683
• MDL number: MFCD00036193
• Beilstein/REAXYS Number: 3832841

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: penicillin & derivatives
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• SMILES string: [K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
• InChI: 1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
• InChI key: IYNDLOXRXUOGIU-LQDWTQKMSA-M

Opis

General description

Penicillin G potassium is a natural β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting transpeptidase enzymes. It is effective against non-β-lactamase-producing Gram-positive organisms. The USP standard facilitates microbiological potency tests and purity analysis.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Wzorzec referencyjny penicyliny G potasowej USP, przeznaczony do stosowania w określonych testach jakości i oznaczeniach, jak określono w kompendiach USP. Również do użytku z monografiami USP, takimi jak:

• Penicylamina
• Penicylina G benzatynowa
• Penicylina G benzatynowa i penicylina G prokainowa w zawiesinie do wstrzykiwań
• Penicylina G benzatynowa zawiesina do wstrzykiwań
• Penicylina G potasowa
• Penicylina G potasowa do wstrzykiwań
• Penicylina G potasowa do sporządzania roztworu doustnego

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Other Notes

Ten produkt jest częścią programu USP Biologics.

Sales restrictions may apply.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• Hazard Classifications: Skin Sens. 1
• Klasa składowania: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364