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Merck

1225281

USP

Dorzolamide hydrochloride

United States Pharmacopeia (USP) Reference Standard

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200 MG

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1910,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C10H16N2O4S3 · HCl
Numer CAS:
130693-82-2
Masa cząsteczkowa:
360.90
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749667
MDL number:
MFCD00884659
Beilstein/REAXYS Number:
5896026

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grade

pharmaceutical primary standard

API family

dorzolamide

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

InChI

1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1

InChI key

OSRUSFPMRGDLAG-QMGYSKNISA-N

Gene Information

human ... CA2(760)

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Ta pozycja
BP1069Y0000726PHR1925
Dorzolamide hydrochloride United States Pharmacopeia (USP) Reference Standard

USP

1225281

Dorzolamide hydrochloride

Dorzolamide hydrochloride British Pharmacopoeia (BP) Reference Standard

BP1069

Dorzolamide hydrochloride

Dorzolamide hydrochloride European Pharmacopoeia (EP) Reference Standard

Y0000726

Dorzolamide hydrochloride

Dorzolamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1925

Dorzolamide hydrochloride

manufacturer/tradename

USP

manufacturer/tradename

BP

manufacturer/tradename

EDQM

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

format

neat

format

neat

format

neat

format

-

API family

dorzolamide

API family

dorzolamide

API family

dorzolamide

API family

dorzolamide

Gene Information

human ... CA2(760)

Gene Information

human ... CA2(760)

Gene Information

human ... CA2(760)

Gene Information

human ... CA2(760)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dorzolamide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Dorzolamide Hydrochloride and Timolol Maleate Ophthalmic Solution
  • Dorzolamide Hydrochloride Ophthalmic Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.
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comparable product

Numer produktu
Opis
Cennik

related product

Numer produktu
Opis
Cennik

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H373

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2

target_organs

Central nervous system,Gastrointestinal tract,Bone,Blood,Bladder

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

M F Sugrue
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 12(3), 363-376 (1996-01-01)
Dorzolamide hydrochloride (S,S-5,6-dihydro-4H-4-ethylamino-6-methylthieno [2,3-b]thiopyran-2-sulfonamide-7,7-dioxide HCl; MK-507; L-671,152) is a water-soluble, potent inhibitor of human carbonic anhydrase isoenzymes II and IV in vitro, the respective IC50 values being 0.18 nM and 6.9 nM. In contrast, it was found to be a
Göktuğ Seymenoğlu et al.
Journal of glaucoma, 24(2), 111-116 (2013-06-29)
To compare the efficacy of fixed combinations of dorzolamide-timolol (FCDT) and brimonidine-timolol (FCBT) in patients with intraocular pressure (IOP) elevations after intravitreal triamcinolone acetonide (IVTA) injections. This was a prospective, randomized, open-label study. Patients who received IVTA injections due to
Masamichi Fukuda et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 31(1), 57-60 (2014-10-11)
We investigated the transcorneal penetration of commercial ophthalmic formulations containing timolol maleate in rabbit eyes. One drop (30 μL) of each ophthalmic solution (Xalacom(®), DuoTrav(®), Cosopt(®), and Timoptol(®)) was administered to the conjunctival sac of the rabbits' eyes and the
Azza A Hasan
Pharmaceutical development and technology, 19(6), 748-754 (2013-08-24)
The objective of this work was to formulate and characterize non-ionic surfactant vesicles (niosomes) as an ocular carrier of dorzolamide hydrochloride (Dorzo); one of the antiglaucoma drugs. Niosomes were prepared of Cholesterol (Chol) with sorbitan monoesters (Span 20, 40, 60)

Numer pozycji handlu globalnego

SKUNUMER GTIN
1225281-200MG04061838721341

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